(Q44007768)

English

Hedgehog signaling regulates brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas

scientific article published on 11 September 2008

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 November 2017

Hedgehog signaling regulates brain tumor-initiating cell proliferation and portends shorter survival for patients with PTEN-coexpressing glioblastomas (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

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author name string

Qijin Xu

1

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Europe PubMed Central

PubMed publication ID

28 November 2017

Xiangpeng Yuan

2

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

Gentao Liu

3

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

Keith L Black

4

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

John S Yu

5

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Europe PubMed Central

PubMed publication ID

28 November 2017

publication date

11 September 2008

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Europe PubMed Central

PubMed publication ID

28 November 2017

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Europe PubMed Central

PubMed publication ID

28 November 2017

26

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Europe PubMed Central

PubMed publication ID

28 November 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

3018-3026

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

Identification of human brain tumour initiating cells

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Prostate cancer stem/progenitor cells: identification, characterization, and implications.

1 reference

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

1 reference

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Identification and expansion of human colon-cancer-initiating cells

1 reference

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Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity

1 reference

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Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

1 reference

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

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Malignant astrocytic glioma: genetics, biology, and paths to treatment

1 reference

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Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

1 reference

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21 January 2018

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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

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A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

1 reference

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PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling

1 reference

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Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma

1 reference

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21 January 2018

HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

1 reference

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Defining the role of mTOR in cancer

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Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

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21 January 2018

In vivo antitumor effect of the mTOR inhibitor CCI-779 and gemcitabine in xenograft models of human pancreatic cancer

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Decreased levels of hypoxic cells in gefitinib treated ER+ HER-2 overexpressing MCF-7 breast cancer tumors are associated with hyperactivation of the mTOR pathway: therapeutic implications for combination therapy with rapamycin.

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Identification of molecular subtypes of glioblastoma by gene expression profiling

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Ligand-dependent activation of the hedgehog pathway in glioma progenitor cells

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

grb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs.

1 reference

https://api.crossref.org/works/10.1634%2FSTEMCELLS.2008-0459

21 January 2018

Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.

1 reference

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21 January 2018

Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study

1 reference

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Epidermal growth factor receptor and Ink4a/Arf

1 reference

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21 January 2018

Identifiers

10.1634/STEMCELLS.2008-0459

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

ResearchGate publication ID

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