(Q44009060)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034365%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Formation and longevity of idarubicin-induced DNA topoisomerase II cleavable complexes in K562 human leukaemia cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034365%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

4

1 reference

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9 November 2019

author name string

Elaine Willmore

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034365%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Fiona Errington

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034365%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Michael J Tilby

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034365%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

1 May 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034365%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

published in

Biochemical Pharmacology

1 reference

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9 November 2019

volume

63

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034365%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

10

1 reference

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9 November 2019

page(s)

1807-1815

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034365%20AND%20SRC:MED&resulttype=core&format=json

Clinical applications of anticancer drugs targeted to topoisomerase II

9 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

The use of an all oral chemotherapy (idarubicin and etoposide) in the treatment of acute myeloid leukaemia in the elderly: a report of toxicity and efficacy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Correlation between the kinetics of anthracycline uptake and the resistance factor in cancer cells expressing the multidrug resistance protein or the P-glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

The relative importance of passive and P-glycoprotein mediated anthracycline efflux from multidrug-resistant cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Eukaryotic DNA topoisomerase II beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

DNA topoisomerase IIbeta and neural development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Murine transgenic cells lacking DNA topoisomerase IIbeta are resistant to acridines and mitoxantrone: analysis of cytotoxicity and cleavable complex formation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Nuclear distribution of human DNA topoisomerase IIbeta: a nuclear targeting signal resides in the 116-residue C-terminal tail.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

A novel mechanism of cell killing by anti-topoisomerase II bisdioxopiperazines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Mapping of DNA topoisomerase II poisons (etoposide, clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Cytotoxicity of anthracyclines: correlation with cellular uptake, intracellular distribution and DNA binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Anthracyclines and their C-13 alcohol metabolites: growth inhibition and DNA damage following incubation with human tumor cells in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Effect of PSC 833 on the cytotoxicity of idarubicin and idarubicinol in multidrug-resistant K562 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Pharmacokinetics of idarubicin (4-demethoxydaunorubicin; IMI-30; NSC 256439) following intravenous and oral administration in patients with advanced cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Relationship between lethal effects and topoisomerase II-mediated double-stranded DNA breaks produced by anthracyclines with different sequence specificity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2 beta construct allows the study of topoisomerase II beta inhibitors in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Cell death induced by topoisomerase-targeted drugs: more questions than answers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Susceptibility of idarubicin, daunorubicin, and their C-13 alcohol metabolites to transport-mediated multidrug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino) methanesulfon-m-anisidide and adriamycin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

Formation, resealing and persistence of DNA breaks produced by 4-demethoxydaunorubicin in P388 leukemia cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2900920-6

10.1016/S0006-2952(02)00920-6

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12034365%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference