(Q44038198)

English

Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12079385%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12079385%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

protein structure

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crystal structure

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based on heuristic

inferred from title

3

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10 November 2019

Núria Verdaguer

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12079385%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Senena Corbalan

2

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10 November 2019

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Wendy F Ochoa

1

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10 November 2019

José A Rodríguez-Alfaro

4

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10 November 2019

Juan C Gómez-Fernández

5

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10 November 2019

Ignacio Fita

6

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10 November 2019

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1 July 2002

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10 November 2019

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15

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Journal of Molecular Biology

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10 November 2019

320

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10 November 2019

2

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10 November 2019

277-291

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10 November 2019

Protein kinase C--a question of specificity

1 reference

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Protein kinase C: a paradigm for regulation of protein function by two membrane-targeting modules

1 reference

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Phosphatidyl-L-serine is necessary for protein kinase C's high-affinity interaction with diacylglycerol-containing membranes

1 reference

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7 January 2021

Lipid structure and not membrane structure is the major determinant in the regulation of protein kinase C by phosphatidylserine.

1 reference

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7 January 2021

The C2 domain calcium-binding motif: structural and functional diversity

1 reference

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7 January 2021

C2-domains, structure and function of a universal Ca2+-binding domain

1 reference

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7 January 2021

Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold

1 reference

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7 January 2021

Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C

1 reference

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7 January 2021

A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1

1 reference

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7 January 2021

Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2

1 reference

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7 January 2021

Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+

1 reference

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7 January 2021

Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine

1 reference

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7 January 2021

Ca2+ binding to synaptotagmin: how many Ca2+ ions bind to the tip of a C2-domain?

1 reference

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7 January 2021

Synaptotagmin I functions as a calcium regulator of release probability

1 reference

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7 January 2021

Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins

1 reference

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7 January 2021

Ca2+-signaling cycle of a membrane-docking C2 domain

1 reference

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7 January 2021

Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I

1 reference

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7 January 2021

The C2 domain of protein kinase calpha is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane

1 reference

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7 January 2021

Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.

1 reference

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7 January 2021

Mutagenesis of the C2 domain of protein kinase C-alpha. Differential roles of Ca2+ ligands and membrane binding residues

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7 January 2021

A structure-function study of the C2 domain of cytosolic phospholipase A2. Identification of essential calcium ligands and hydrophobic membrane binding residues.

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7 January 2021

Mechanism of the apparent cooperativity in the interaction of protein kinase C with phosphatidylserine.

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7 January 2021

Membrane binding kinetics of protein kinase C betaII mediated by the C2 domain

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7 January 2021

A novel phosphatidylserine-binding peptide motif defined by an anti-idiotypic monoclonal antibody. Localization of phosphatidylserine-specific binding sites on protein kinase C and phosphatidylserine decarboxylase

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7 January 2021

Regulation of protein kinase C betaII by its C2 domain

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7 January 2021

A putative phosphatidylserine binding motif is not involved in the lipid regulation of protein kinase C.

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7 January 2021

Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity.

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7 January 2021

Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals

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Determination of the calcium-binding sites of the C2 domain of protein kinase Calpha that are critical for its translocation to the plasma membrane

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AMoRe: an automated package for molecular replacement

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Identifiers

10.1016/S0022-2836(02)00464-3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12079385%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12079385%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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