(Q44038364)

English

Hammerhead ribozyme against gamma-glutamylcysteine synthetase attenuates resistance to ionizing radiation and cisplatin in human T98G glioblastoma cells

scientific article published in June 2002

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Hammerhead ribozyme against gamma-glutamylcysteine synthetase attenuates resistance to ionizing radiation and cisplatin in human T98G glioblastoma cells (English)

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

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1 reference

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author name string

Masaharu Tani

1

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Shinji Goto

2

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Kensaku Kamada

3

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Katsuharu Mori

4

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Yoshishige Urata

5

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Yoshito Ihara

6

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Hiroshi Kijima

7

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Yoshito Ueyama

8

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Shobu Shibata

9

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Takahito Kondo

10

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

language of work or name

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publication date

1 June 2002

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

number of pages

7

1 reference

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inferred from page(s)

Japanese Journal of Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

93

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

6

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

716-722

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

Hammerhead ribozyme against gamma-glutamylcysteine synthetase sensitizes human colonic cancer cells to cisplatin by down-regulating both the glutathione synthesis and the expression of multidrug resistance proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Reversal of cisplatin and multidrug resistance by ribozyme-mediated glutathione suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Overexpression of glutathione S-transferase pi enhances the adduct formation of cisplatin with glutathione in human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

The molecular basis of a case of gamma-glutamylcysteine synthetase deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Redox regulation of c-Jun DNA binding by reversible S-glutathiolation.

1 reference

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10 July 2018

Overexpression of gamma-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Overexpression of the regulatory subunit of gamma-glutamylcysteine synthetase in HeLa cells increases gamma-glutamylcysteine synthetase activity and confers drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Hammerhead ribozymes against gamma-glutamylcysteine synthetase mRNA down-regulate intracellular glutathione concentration of mouse islet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Frequent coexpression of MRP/GS-X pump and gamma-glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Cisplatin induces radioprotection in human T98G glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

The interaction of buthionine sulphoximide (BSO) and the topoisomerase I inhibitor CPT-11.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Relation of oxidative stress and glutathione synthesis to CD95(Fas/APO-1)-mediated apoptosis of adult T cell leukemia cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

In vitro split-dose recovery of glioblastoma multiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

gamma-Glutamylcysteine synthetase and active transport of glutathione S-conjugate are responsive to heat shock in K562 erythroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Ribozyme-mediated reversal of the multidrug-resistant phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Evidence for altered regulation of gamma-glutamylcysteine synthetase gene expression among cisplatin-sensitive and cisplatin-resistant human ovarian cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Amino acid sequence of rat kidney gamma-glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

10 July 2018

Expression of enzymes and oncogene induced after radiotherapy and/or chemotherapy in patients with brain tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

15 August 2018

Nuclear factor kappa B dependent induction of gamma glutamylcysteine synthetase by ionizing radiation in T98G human glioblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

15 August 2018

Co-ordinated over-expression of the MRP and gamma-glutamylcysteine synthetase genes, but not MDR1, correlates with doxorubicin resistance in human malignant mesothelioma cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

15 August 2018

Investigation of chemoresistance-related genes mRNA expression for selecting anticancer agents in successful adjuvant chemotherapy for a case of recurrent glioblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

15 August 2018

Simple RNA enzymes with new and highly specific endoribonuclease activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5927042

15 August 2018

Overexpression of the regulatory subunit of γ-glutamylcysteine synthetase in HeLa cells increases γ-glutamylcysteine synthetase activity and confers drug resistance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2002.TB01311.X

21 January 2018

Glutathione downregulates the phosphorylation of I kappa B: autoloop regulation of the NF-kappa B-mediated expression of NF-kappa B subunits by TNF-alpha in mouse vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12079521

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmentation of transport for cisplatin-glutathione adduct in cisplatin-resistant cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12079521

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxic effects of extended glutathione depletion by buthionine sulfoximine on murine mammary carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12079521

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-expression of gamma-glutamylcysteine synthetase sub-units in response to cisplatin and doxorubicin in human cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12079521

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for the selective modification of glutathione metabolism and study of glutathione transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/12079521

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1349-7006.2002.TB01311.X

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

6 July 2018

http://europepmc.org/abstract/PMC/5927042

ResearchGate publication ID

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