(Q44041374)

29 November 2017

title

Evidence for a perforin-mediated mechanism controlling cardiac inflammation in Trypanosoma cruzi infection (English)

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29 November 2017

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10

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29 November 2017

author name string

Andrea Henriques-Pons

1

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29 November 2017

Gabriel M Oliveira

2

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29 November 2017

Mauricio M Paiva

3

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29 November 2017

Alexandre F S Correa

4

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29 November 2017

Marcos M Batista

5

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29 November 2017

Rodrigo C Bisaggio

6

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29 November 2017

Chau-Ching Liu

7

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29 November 2017

Vinicius Cotta-De-Almeida

8

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29 November 2017

Claudia M L M Coutinho

9

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29 November 2017

Tania C Araujo-Jorge

11

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29 November 2017

publication date

1 April 2002

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International Journal of Experimental Pathology

29 November 2017

published in

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29 November 2017

volume

83

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29 November 2017

issue

2

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29 November 2017

page(s)

67-79

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Nitric oxide can inhibit apoptosis or switch it into necrosis

29 November 2017

cites work

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29 September 2018

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Trypanosoma cruzi: roles for perforin-dependent and perforin-independent immune mechanisms in acute resistance.

29 September 2018

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Perforin: more than just an effector molecule

29 September 2018

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A role for perforin in downregulating T-cell responses during chronic viral infection.

29 September 2018

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Enhanced antibody and cytokine responses to influenza viral antigens in perforin-deficient mice

29 September 2018

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Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.

29 September 2018

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The relative contribution of antibody production and CD8+ T cell function to immune control of Trypanosoma cruzi

29 September 2018

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29 September 2018

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Cytokines and cardiomyocyte death

29 September 2018

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Perforin-mediated cytolysis plays a limited role in host resistance to Toxoplasma gondii.

29 September 2018

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Trypanosoma cruzi: resistance to the pore forming protein of cytotoxic lymphocytes--perforin

29 September 2018

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The course of Mycobacterium tuberculosis infection in the lungs of mice lacking expression of either perforin- or granzyme-mediated cytolytic mechanisms

29 September 2018

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Innate immunity to Toxoplasma gondii is influenced by gender and is associated with differences in interleukin-12 and gamma interferon production

29 September 2018

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Evidence for CD8+ T-cell immunity to murine rotavirus in the absence of perforin, fas, and gamma interferon.

29 September 2018

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Trypanosoma cruzi: IL-10, TNF, IFN-gamma, and IL-12 regulate innate and acquired immunity to infection.

29 September 2018

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Decreased tumor surveillance in perforin-deficient mice

29 September 2018

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Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection

29 September 2018

1 reference

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The roles of perforin- and Fas-dependent cytotoxicity in protection against cytopathic and noncytopathic viruses

29 September 2018

1 reference

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Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells

29 September 2018

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CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity.

29 September 2018

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Perforin: structure and function

29 September 2018

1 reference

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The challenge of chagasic cardiomyopathy. The pathologic roles of autonomic abnormalities, autoimmune mechanisms and microvascular changes, and therapeutic implications

29 September 2018

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The role of the innate immune response in Th1 cell development following Leishmania major infection.

29 September 2018

1 reference

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Immune function in mice lacking the perforin gene

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517672

Cytotoxic lymphocyte granzymes trigger a target cell internal disintegration pathway leading to cytolysis and DNA breakdown.

29 September 2018

1 reference

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The effect of immuno-depression due to neonatal thymectomy on infections with trypanosoma cruzi in mice

29 September 2018

1 reference

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Experimental infection with Trypanosoma cruzi (Chagas' disease): a model of acute and chronic myocardiopathy

29 September 2018

1 reference

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Purified perforin induces target cell lysis but not DNA fragmentation

29 September 2018

1 reference

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The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities

29 September 2018

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Pathophysiological insights into the cardiomyopathy of Chagas' disease

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517672

Influence of Trypanosoma cruzi strain on the pathogenesis of chronic myocardiopathy in mice

29 September 2018

1 reference

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Permeability alteration of the sarcolemmal membrane, particularly at the site of macrophage contact, in experimental chronic Trypanosoma cruzi myocarditis in mice

29 September 2018

1 reference

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Susceptibility of beta 2-microglobulin-deficient mice to Trypanosoma cruzi infection

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517672

Efficient Nuclear Targeting of Granzyme B and the Nuclear Consequences of Apoptosis Induced by Granzyme B and Perforin Are Caspase-dependent, but Cell Death Is Caspase-independent

29 September 2018

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Polyclonal Lymphocyte Responses to Murine Trypanosoma cruzi Infection

21 January 2018

1 reference

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https://api.crossref.org/works/10.1046%2FJ.1365-2613.2002.00215.X

Parasitic load increases and myocardial inflammation decreases in Trypanosoma cruzi-infected mice after inactivation of helper T cells

21 January 2018

3 references

Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2613.2002.00215.X

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517672

1 December 2018

12 December 2020

Enzymatic markers of heart lesion in mice infected with Trypanosoma cruzi and submitted to benznidazole chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517672

Outcome of infection with different strains of Trypanosoma cruzi in mice lacking CD4 and/or CD8

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517672

Polyclonal lymphocyte responses to murine Trypanosoma cruzi infection. I. Quantitation of both T- and B-cell responses

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517672

Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517672

Studies of the thymus in Chagas' disease: III. Colonization of the thymus and other lymphoid organs of adult and newborn mice by Trypanosoma cruzi

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2517672

Trypanosoma cruzi: the effect of variations in experimental conditions on the levels of macrophage infection in vitro

1 December 2018

1 reference

12 December 2020

Perforin/Fas-ligand double deficiency is associated with macrophage expansion and severe pancreatitis

1 reference

12 December 2020

A role for perforin in activation-induced T cell death in vivo: increased expansion of allogeneic perforin-deficient T cells in SCID mice

1 reference

12 December 2020

Nitric oxide induces apoptotic death of cardiomyocytes via a cyclic-GMP-dependent pathway

1 reference

12 December 2020

Homeostatic regulation of CD8+ T cells by perforin

1 reference

12 December 2020

10.1046/J.1365-2613.2002.00215.X

Identifiers

DOI

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29 November 2017

0 references

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