(Q44041873)

English

Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain.

scientific article published on 25 June 2002

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scholarly article

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10 November 2019

Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084708%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Alzheimer's disease

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phosphorylation

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Nicola Zambrano

5

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10 November 2019

author name string

Claudio Russo

1

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10 November 2019

Virginia Dolcini

2

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10 November 2019

Serena Salis

3

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10 November 2019

Valentina Venezia

4

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10 November 2019

Tommaso Russo

6

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10 November 2019

Gennaro Schettini

7

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10 November 2019

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publication date

25 June 2002

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10 November 2019

Journal of Biological Chemistry

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10 November 2019

277

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10 November 2019

35282-35288

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10 November 2019

38

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10 November 2019

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Diversity in protein recognition by PTB domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

The disabled 1 phosphotyrosine-binding domain binds to the internalization signals of transmembrane glycoproteins and to phospholipids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Amino-terminal modification and tyrosine phosphorylation of [corrected] carboxy-terminal fragments of the amyloid precursor protein in Alzheimer's disease and Down's syndrome brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part XI. Clinical milestones in patients with Alzheimer's disease followed over 3 years

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Intracellular mechanisms mediating the neuronal death and astrogliosis induced by the prion protein fragment 106-126.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Presenilin-1 mutations in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Intracellular A beta 1-42 aggregates stimulate the accumulation of stable, insoluble amyloidogenic fragments of the amyloid precursor protein in transfected cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Alzheimer beta/A4-amyloid precursor protein: evidence for putative amyloidogenic fragment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Alternative expression of Shc family members in nerve-injured motoneurons.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Inflammation and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Differential APP gene expression in rat cerebral cortex, meninges, and primary astroglial, microglial and neuronal cultures.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Pertussis toxin-sensitive and -insensitive thrombin stimulation of Shc phosphorylation and mitogenesis are mediated through distinct pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Serine proteases and brain damage - is there a link?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Thrombin accumulation in brains of patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Protease-activated receptors: sentries for inflammation?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid beta and cytoplasmic domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Nicastrin binds to membrane-tethered Notch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Coagulation factor XIa cleaves the RHDS sequence and abolishes the cell adhesive properties of the amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110785200

21 January 2018

Identifiers

10.1074/JBC.M110785200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084708%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12084708%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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