(Q44049211)

English

Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A.

scientific article published on 2 July 2002

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

reperfusion injury

1 reference

based on heuristic

inferred from title

Andrew P Halestrap

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

Samantha J Clarke

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

language of work or name

0 references

publication date

2 July 2002

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

277

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

38

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

34793-34799

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Mitochondria and cell death.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Breaking the mitochondrial barrier

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

A mitochondrial perspective on cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

The mechanism of action of cyclosporin A and FK506

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Calcineurin: form and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Calcium, calcineurin, and the control of transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Sanglifehrin A, a novel cyclophilin-binding compound showing immunosuppressive activity with a new mechanism of action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Sanglifehrin A, a novel cyclophilin-binding immunosuppressant, inhibits IL-2-dependent T cell proliferation at the G1 phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Inhibition of cell cycle progression by the novel cyclophilin ligand sanglifehrin A is mediated through the NFkappa B-dependent activation of p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

A continuous spectrophotometric direct assay for peptidyl prolyl cis-trans isomerases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202191200

21 January 2018

Sanglifehrins A, B, C and D, Novel Cyclophilin-binding Compounds Isolated from Streptomyces sp. A92-308110. I. Taxonomy, Fermentation, Isolation and Biological Activity.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.52.466

Identifiers

10.1074/JBC.M202191200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12095984%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44049211&oldid=2127242358"