(Q44060415)

29 November 2017

title

Mutant frequency and mutational spectra in the Tk and Hprt genes of N-ethyl-N-nitrosourea-treated mouse lymphoma cellsdagger (English)

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29 November 2017

Tao Chen

1

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29 November 2017

Karen Harrington-Brock

series ordinal

2

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29 November 2017

Martha M Moore

series ordinal

3

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29 November 2017

publication date

1 January 2002

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Environmental and Molecular Mutagenesis

29 November 2017

published in

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29 November 2017

volume

39

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29 November 2017

issue

4

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29 November 2017

page(s)

296-305

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Statistical test for the comparison of samples from mutational spectra

29 November 2017

cites work

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Induction of 6-thioguanine-resistant lymphocytes in Fischer 344 rats following in vivo exposure to N-ethyl-N-nitrosourea and cyclophosphamide.

21 January 2018

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T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood

21 January 2018

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Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells

21 January 2018

1 reference

Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control cultures

21 January 2018

1 reference

Computer program for the analysis of mutational spectra: application to p53 mutations.

21 January 2018

1 reference

Validation and characterization of the L5178Y/TK+/- mouse lymphoma mutagen assay system

21 January 2018

1 reference

Molecular aspects of chemical mutagenesis in L5178Y/tk +/- mouse lymphoma cells

21 January 2018

1 reference

Locus specificity of mutagenicity of 2,4-diaminotoluene in both L5178Y mouse lymphoma and AT3-2 Chinese hamster ovary cells

21 January 2018

1 reference

Sequence specific mutations induced by N-nitrosodimethylamine at two marker loci in metabolically competent human lymphoblastoid cells

21 January 2018

1 reference

Molecular analysis of mutations induced in human cells by N-ethyl-N-nitrosourea

21 January 2018

1 reference

Site-specific mutagenesis by O6-alkylguanines located in the chromosomes of mammalian cells: influence of the mammalian O6-alkylguanine-DNA alkyltransferase

21 January 2018

1 reference

Analysis of ENU-induced mutations at the Adh locus in Drosophila melanogaster.

21 January 2018

1 reference

Characterization of the murine thymidine kinase-encoding gene and analysis of transcription start point heterogeneity

21 January 2018

1 reference

Recombinagenic activity of the phorbol ester 12-O-Metradecanoylphorbol-13-acetate in human lymphoblastoid cells

21 January 2018

1 reference

Mutational specificity of alkylating agents and the influence of DNA repair

21 January 2018

1 reference

Cytogenetic analysis of the L5178Y/TK+/− → TK−/− mouse lymphoma mutagenesis assay system

21 January 2018

1 reference

In vitro mammalian mutagenesis as a model for genetic lesions in human cancer

21 January 2018

1 reference

The dose-response relationship for ethyl methanesulfonate-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells

21 January 2018

1 reference

A method to quantify spontaneous and in vivo induced thioguanine-resistant mouse lymphocytes

21 January 2018

1 reference

Use of shuttle vectors to study the molecular processing of defined carcinogen-induced DNA damage: mutagenicity of single O4-ethylthymine adducts in HeLa cells

21 January 2018

1 reference

Locus specificity for mutation induction in human cells exposed to accelerated heavy ions.

21 January 2018

1 reference

Sequence analysis of tka(-)-1 and tkb(+)-1 alleles in L5178Y tk+/- mouse-lymphoma cells and spontaneous tk-/- mutants

21 January 2018

1 reference

Analysis of large and small colony L5178Y tk-/- mouse lymphoma mutants by loss of heterozygosity (LOH) and by whole chromosome 11 painting: detection of recombination

21 January 2018

1 reference

Specificities of human, rat and E. coli O6-methylguanine-DNA methyltransferases towards the repair of O6-methyl and O6-ethylguanine in DNA.

21 January 2018

1 reference

Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene

21 January 2018

1 reference

Mutagenicity of 1,3-butadiene at the Hprt locus of T-lymphocytes following inhalation exposures of female mice and rats.

21 January 2018

1 reference

Analysis of in vivo mutation induced by N-ethyl-N-nitrosourea in the hprt gene of rat lymphocytes

21 January 2018

1 reference

Analysis of trifluorothymidine-resistant (TFTr) mutants of L5178Y/TK+/- mouse lymphoma cells

21 January 2018

1 reference

Mutagenicity and clastogenicity of acrylamide in L5178Y mouse lymphoma cells

21 January 2018

1 reference

Differential mutant quantitation at the mouse lymphoma tk and CHO hgprt loci

21 January 2018

1 reference

DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea

21 January 2018

1 reference

A review of the genotoxicity of 1-ethyl-1-nitrosourea

21 January 2018

1 reference

Mutational spectrum at the Hprt locus in splenic T cells of B6C3F1 mice exposed to N-ethyl-N-nitrosourea

21 January 2018

1 reference

Enumeration of 6-thioguanine-resistant T-lymphocytes in the peripheral blood of nonhuman primates (cynomolgus monkeys).

21 January 2018

1 reference

Identification and chromosomal assignment of two heterozygous mutations in the Trp53 gene in L5178Y/Tk(+/-)-3.7.2C mouse lymphoma cells

21 January 2018

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Molecular analysis of in vivo mutations induced by N-ethyl-N-nitrosourea in the autosomal Tk and the X-linked Hprt genes of mouse lymphocytes

21 January 2018

1 reference

Cytogenetic distinction between the TK+ and TK- chromosomes in the L5178Y TK+/- 3.7.2C mouse-lymphoma cell line

21 January 2018

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Chromosome 11 aberrations in small colony L5178Y TK-/- mutants early in their clonal history

21 January 2018

1 reference

AT base pairs are the main target for mutations at the hprt locus of rat skin fibroblasts exposed in vitro to the monofunctional alkylating agent N-ethyl-N-nitrosourea

21 January 2018

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The quantitation of TK-/- and HGPRT- mutants of L5178Y/TK+/- mouse lymphoma cells at varying times post-treatment

21 January 2018

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A comparison of the genotoxicity of ethylnitrosourea and ethyl methanesulfonate in lacZ transgenic mice (Muta Mouse)

21 January 2018

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Somatic mutations at a heterozygous autosomal locus in human cells occur more frequently by allele loss than by intragenic structural alterations

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/EM.10075

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29 November 2017

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