(Q44060440)

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Preferential action of gabapentin and pregabalin at P/Q-type voltage-sensitive calcium channels: inhibition of K+-evoked [3H]-norepinephrine release from rat neocortical slices

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Europe PubMed Central

PubMed publication ID

29 November 2017

Preferential action of gabapentin and pregabalin at P/Q-type voltage-sensitive calcium channels: inhibition of K+-evoked [3H]-norepinephrine release from rat neocortical slices (English)

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Europe PubMed Central

PubMed publication ID

29 November 2017

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author name string

David J Dooley

1

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Europe PubMed Central

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29 November 2017

Cindy M Donovan

2

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29 November 2017

Wolfgang P Meder

3

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29 November 2017

Steven Z Whetzel

4

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29 November 2017

publication date

1 September 2002

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29 November 2017

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29 November 2017

45

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29 November 2017

3

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29 November 2017

171-190

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PubMed publication ID

29 November 2017

Cloning and deletion mutagenesis of the alpha2 delta calcium channel subunit from porcine cerebral cortex. Expression of a soluble form of the protein that retains [3H]gabapentin binding activity

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Characterization of the dihydropyridine binding sites of rat neocortical synaptosomes and microvessels.

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Inhibition of K(+)-evoked glutamate release from rat neocortical and hippocampal slices by gabapentin

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Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices

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The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel

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The non-dihydropyridine L-type voltage-sensitive calcium channel activator FPL 64176 enhances K(+)-evoked efflux of [3H]norepinephrine from rat neocortical slices.

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Tissue-specific expression and gabapentin-binding properties of calcium channel alpha2delta subunit subtypes

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Characterization of Ca(2+)-channels responsible for K(+)-evoked [(3)H]noradrenaline release from rat brain cortex synaptosomes and their response to amyotrophic lateral sclerosis IgGs.

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Localization of [3H]gabapentin to a novel site in rat brain: autoradiographic studies.

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Neuronal distribution and functional characterization of the calcium channel alpha2delta-2 subunit

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Characterization of the binding of omega-conopeptides to different classes of non-L-type neuronal calcium channels

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P/Q-type Ca2+ channel defects in migraine, ataxia and epilepsy.

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Glutamate receptors in the mammalian central nervous system

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CSF amino acids and plasma-CSF amino acid ratios in adults

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Gabapentin-lactam, a close analogue of the anticonvulsant gabapentin, exerts convulsant activity in amygdala kindled rats

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Gabapentin inhibits calcium currents in isolated rat brain neurons.

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Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies.

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A summary of mechanistic hypotheses of gabapentin pharmacology

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Effects of antagonists to high-threshold calcium channels upon spinal mechanisms of pain, hyperalgesia and allodynia

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Subunit interaction sites in voltage-dependent Ca2+ channels: role in channel function.

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Presynaptic glutamate receptors regulate noradrenaline release from isolated nerve terminals

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Presynaptic inhibition of elicited neurotransmitter release

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Electrophysiological and pharmacological properties of the human brain type IIA Na+ channel expressed in a stable mammalian cell line

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Identifiers

10.1002/SYN.10094

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

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