(Q44071200)

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Synthesis and initial structure-activity relationships of a novel series of imidazolo[1,2-a]pyrimid-5-ones as potent GnRH receptor antagonists

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Europe PubMed Central

PubMed publication ID

29 November 2017

Synthesis and initial structure-activity relationships of a novel series of imidazolo[1,2-a]pyrimid-5-ones as potent GnRH receptor antagonists (English)

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Europe PubMed Central

PubMed publication ID

29 November 2017

author name string

Keith M Wilcoxen

1

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Europe PubMed Central

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29 November 2017

Yun Fei Zhu

2

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29 November 2017

Patrick J Connors

3

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29 November 2017

John Saunders

4

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29 November 2017

Timothy D Gross

5

1 reference

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29 November 2017

Yinghong Gao

6

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29 November 2017

Greg J Reinhart

7

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29 November 2017

R Scott Struthers

8

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29 November 2017

Chen Chen

9

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29 November 2017

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publication date

1 August 2002

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29 November 2017

Bioorganic & Medicinal Chemistry Letters

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29 November 2017

12

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29 November 2017

16

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29 November 2017

2179-2183

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29 November 2017

Structure of the porcine LH- and FSH-releasing hormone. I. The proposed amino acid sequence

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Primary structure of the ovine hypothalamic luteinizing hormone-releasing factor (LRF) (LH-hypothalamus-LRF-gas chromatography-mass spectrometry-decapeptide-Edman degradation).

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Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor

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Synthetic analogs of luteinizing hormone releasing hormone (LH-RH) substituted in position 6 and 10.

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Leuprolide versus diethylstilbestrol for metastatic prostate cancer

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Gonadotropin-releasing hormone analog design. Structure-function studies toward the development of agonists and antagonists: rationale and perspective

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Discovery of a novel, potent, and orally active nonpeptide antagonist of the human luteinizing hormone-releasing hormone (LHRH) receptor

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A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptor

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Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity

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Initial structure-activity relationship studies of a novel series of pyrrolo[1,2-a]pyrimid-7-ones as GnRH receptor antagonists

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A novel synthesis of 2-arylpyrrolo[1,2-a]pyrimid-7-ones and their structure-activity relationships as potent GnRH receptor antagonists

1 reference

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Design, synthesis and structure-activity relationships of novel imidazolo[1,2-a]pyrimid-5-ones as potent GnRH receptor antagonists

1 reference

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Identifiers

10.1016/S0960-894X(02)00370-0

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Europe PubMed Central

PubMed publication ID

29 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

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