(Q44075413)

English

The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells

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Europe PubMed Central

PubMed publication ID

29 November 2017

The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

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1 reference

ChEBI release 2020-05-28

author name string

Karsten Spiekermann

1

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Florian Faber

2

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Robert Voswinckel

3

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Europe PubMed Central

PubMed publication ID

29 November 2017

Wolfgang Hiddemann

4

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Europe PubMed Central

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29 November 2017

language of work or name

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publication date

1 July 2002

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29 November 2017

Experimental Hematology

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Europe PubMed Central

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29 November 2017

30

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Europe PubMed Central

PubMed publication ID

29 November 2017

7

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Europe PubMed Central

PubMed publication ID

29 November 2017

767-773

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Europe PubMed Central

PubMed publication ID

29 November 2017

Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Angiogenesis and tumor metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The biology of vascular endothelial growth factor

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https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of vascular endothelial growth factor (VEGF) and placenta-derived growth factor (PlGF) in regulating human haemopoietic cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased bone marrow vascularization in patients with acute myeloid leukaemia: a possible role for vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Stable remission after administration of the receptor tyrosine kinase inhibitor SU5416 in a patient with refractory acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Constitutive activation of STAT3 and STAT5 is induced by leukemic fusion proteins with protein tyrosine kinase activity and is sufficient for transformation of hematopoietic precursor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

De novo expression of vascular endothelial growth factor in human pancreatic cancer: evidence for an autocrine mitogenic loop.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The antiangiogenic protein kinase inhibitors SU5416 and SU6668 inhibit the SCF receptor (c-kit) in a human myeloid leukemia cell line and in acute myeloid leukemia blasts

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

TGF-beta inhibits growth and induces apoptosis in leukemic B cell precursors

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel, microcarrier-based in vitro assay for rapid and reliable quantification of three-dimensional cell migration and angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Kit and c-kit mutations in mastocytosis and other hematological diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2802%2900837-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0301-472X(02)00837-8

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

release_ttc4sqxembbthaish4hm2qrva4

1 reference

https://api.fatcat.wiki/v0/release/ttc4sqxembbthaish4hm2qrva4

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

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