(Q44114984)

29 November 2017

title

Weak strand displacement activity enables human DNA polymerase beta to expand CAG/CTG triplet repeats at strand breaks (English)

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29 November 2017

author name string

Michael J Hartenstine

series ordinal

1

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29 November 2017

Myron F Goodman

series ordinal

2

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29 November 2017

John Petruska

series ordinal

3

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29 November 2017

language of work or name

English

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publication date

23 August 2002

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Journal of Biological Chemistry

29 November 2017

published in

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29 November 2017

volume

277

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29 November 2017

issue

44

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29 November 2017

page(s)

41379-41389

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The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders

29 November 2017

cites work

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21 January 2018

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Hairpin properties of single-stranded DNA containing a GC-rich triplet repeat: (CTG)15.

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Trinucleotide repeats that expand in human disease form hairpin structures in vitro

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The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

21 January 2018

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DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro

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Meiotic instability of CAG repeat tracts occurs by double-strand break repair in yeast

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Requirement of mammalian DNA polymerase-beta in base-excision repair.

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Measurement of DNA polymerase beta in skin fibroblast cell lines from patients with ataxia telangiectasia.

21 January 2018

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Mixed spermatogenic germ cell nuclear extracts exhibit high base excision repair activity

21 January 2018

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Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

21 January 2018

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DNA polymerase beta -mediated long patch base excision repair. Poly(ADP-ribose)polymerase-1 stimulates strand displacement DNA synthesis.

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Pausing of DNA synthesis in vitro at specific loci in CTG and CGG triplet repeats from human hereditary disease genes.

21 January 2018

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In vitro expansion of GGC:GCC repeats: identification of the preferred strand of expansion.

21 January 2018

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Deletion errors generated during replication of CAG repeats

21 January 2018

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Dinucleotide repeat expansion catalyzed by bacteriophage T4 DNA polymerase in vitro.

21 January 2018

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Analysis of strand slippage in DNA polymerase expansions of CAG/CTG triplet repeats associated with neurodegenerative disease

21 January 2018

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Expression of human DNA polymerase beta in Escherichia coli and characterization of the recombinant enzyme

21 January 2018

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Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I.

21 January 2018

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Physiological concentrations of purines and pyrimidines

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Replication slippage of different DNA polymerases is inversely related to their strand displacement efficiency

21 January 2018

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DNA polymerase lambda, a novel DNA repair enzyme in human cells.

21 January 2018

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21 January 2018

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21 January 2018

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Triplet repeats form secondary structures that escape DNA repair in yeast

21 January 2018

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Sticky DNA: self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia.

21 January 2018

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Repeat expansion--all in a flap?

21 January 2018

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Reactivity of KB cell deoxyribonucleic acid polymerases .alpha. and .beta. with nicked and gapped deoxyribonucleic acid

21 January 2018

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Hairpin formation during DNA synthesis primer realignment in vitro in triplet repeat sequences from human hereditary disease genes

21 January 2018

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Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation

21 January 2018

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Evidence of founder chromosomes in fragile X syndrome

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M207013200

1 reference

29 November 2017

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