(Q44119079)

English

Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet

scientific article published on 28 August 2002

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 November 2017

Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

hypercholesterolemia

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author name string

Jean Y Chen

1

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Beatriz Levy-Wilson

2

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Sheryl Goodart

3

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

Allen D Cooper

4

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

language of work or name

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publication date

28 August 2002

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Europe PubMed Central

PubMed publication ID

30 November 2017

number of pages

8

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

30 November 2017

277

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Europe PubMed Central

PubMed publication ID

30 November 2017

45

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

42588-42595

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

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1 reference

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Regulation of bile acid biosynthesis

1 reference

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Identification of a nuclear receptor for bile acids

1 reference

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1 reference

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21 January 2018

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

1 reference

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21 January 2018

Role of LXRs in control of lipogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

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Dietary cholesterol and downregulation of cholesterol 7 alpha-hydroxylase and cholesterol absorption in African green monkeys

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Characterization of hepatic-specific regulatory elements in the promoter region of the human cholesterol 7alpha-hydroxylase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Hepatocyte nuclear factor 1 binds to and transactivates the human but not the rat CYP7A1 promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Expression of the human cholesterol 7alpha-hydroxylase gene in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

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Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

1 reference

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Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation.

1 reference

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Characteristics and regulation of bile salt synthesis and secretion by human hepatoma HepG2 cells

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Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Bile acids: natural ligands for an orphan nuclear receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Unexpected inhibition of cholesterol 7 alpha-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Increased production of apolipoprotein B-containing lipoproteins in the absence of hyperlipidemia in transgenic mice expressing cholesterol 7alpha-hydroxylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Plasma cholesterol-predictive equations demonstrate that stearic acid is neutral and monounsaturated fatty acids are hypocholesterolemic.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205117200

21 January 2018

Effects of dietary cholesterol and fatty acids on plasma lipoproteins

1 reference

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21 January 2018

Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M205117200

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 November 2017

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