(Q44132505)

30 November 2017

title

The N termini of focal adhesion kinase family members regulate substrate phosphorylation, localization, and cell morphology (English)

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30 November 2017

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Jill M Dunty

1

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30 November 2017

Michael D Schaller

series ordinal

2

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30 November 2017

language of work or name

English

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publication date

9 September 2002

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Journal of Biological Chemistry

30 November 2017

published in

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30 November 2017

volume

277

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30 November 2017

issue

47

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30 November 2017

page(s)

45644-45654

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Biochemical signals and biological responses elicited by the focal adhesion kinase

30 November 2017

cites work

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The N-termini of FAK and JAKs contain divergent band 4.1 domains

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Lipopolysaccharide induces actin reorganization and tyrosine phosphorylation of Pyk2 and paxillin in monocytes and macrophages

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Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion

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Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions

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Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

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Identification of a new Pyk2 target protein with Arf-GAP activity

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Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

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Signaling through focal adhesion kinase

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Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation

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Focal adhesion targeting: the critical determinant of FAK regulation and substrate phosphorylation

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Paxillin binding is not the sole determinant of focal adhesion localization or dominant-negative activity of focal adhesion kinase/focal adhesion kinase-related nonkinase

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Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

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Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

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Inhibition of pp125FAK in cultured fibroblasts results in apoptosis

21 January 2018

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Induction of apoptosis after expression of PYK2, a tyrosine kinase structurally related to focal adhesion kinase

21 January 2018

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SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells

21 January 2018

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Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins

21 January 2018

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Characterization of the tyrosine kinases RAFTK/Pyk2 and FAK in nerve growth factor-induced neuronal differentiation.

21 January 2018

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Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

21 January 2018

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Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases

21 January 2018

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Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

21 January 2018

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The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity

21 January 2018

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Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

21 January 2018

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SH2- and SH3-mediated interactions between focal adhesion kinase and Src.

21 January 2018

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

21 January 2018

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Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

21 January 2018

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Interactions between two cytoskeleton-associated tyrosine kinases: calcium-dependent tyrosine kinase and focal adhesion tyrosine kinase

21 January 2018

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Rho GTPases and the actin cytoskeleton

21 January 2018

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Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

21 January 2018

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Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells

21 January 2018

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Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'

21 January 2018

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Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

21 January 2018

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Integrins: emerging paradigms of signal transduction

21 January 2018

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Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

21 January 2018

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Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201779200

FAK integrates growth-factor and integrin signals to promote cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201779200

Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201779200

Protection from natural killer cell-mediated lysis by HLA-G expression on target cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M201779200

Paxillin: a focal adhesion-associated adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201779200

Inhibition of osteoclast function by adenovirus expressing antisense protein-tyrosine kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201779200

21 January 2018

Identifiers

DOI

10.1074/JBC.M201779200

1 reference

30 November 2017

1 reference