(Q44139242)

English

T lymphocytes can be effectively recruited for ex vivo and in vivo lysis of AML blasts by a novel CD33/CD3-bispecific BiTE antibody construct.

scientific article published on 26 November 2012

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scholarly article

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18 February 2020

T lymphocytes can be effectively recruited for ex vivo and in vivo lysis of AML blasts by a novel CD33/CD3-bispecific BiTE antibody construct (English)

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18 February 2020

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Stefan W. Krause

12

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18 February 2020

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M Aigner

1

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18 February 2020

J Feulner

2

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18 February 2020

S Schaffer

3

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18 February 2020

R Kischel

4

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18 February 2020

P Kufer

5

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18 February 2020

K Schneider

6

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18 February 2020

A Henn

7

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18 February 2020

B Rattel

8

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18 February 2020

M Friedrich

9

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18 February 2020

P A Baeuerle

10

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18 February 2020

A Mackensen

11

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18 February 2020

publication date

26 November 2012

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18 February 2020

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18 February 2020

27

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18 February 2020

5

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18 February 2020

1107-1115

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18 February 2020

Therapeutic advances in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Correlation between flow cytometric identification of CD33-positive cells and morphological evaluation of myeloblasts in bone marrow of patients with acute myeloblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Antibody-drug conjugates of calicheamicin derivative: gemtuzumab ozogamicin and inotuzumab ozogamicin

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Phase III randomized multicenter study of a humanized anti-CD33 monoclonal antibody, lintuzumab, in combination with chemotherapy, versus chemotherapy alone in patients with refractory or first-relapsed acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Inhibition of acute myeloid leukemia cell growth by mono-specific and bi-specific anti-CD33 x anti-CD64 antibodies

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Effective elimination of acute myeloid leukemic cells by recombinant bispecific antibody derivatives directed against CD33 and CD16.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Tumor regression in cancer patients by very low doses of a T cell-engaging antibody

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

SAR3419: an anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Epitope distance to the target cell membrane and antigen size determine the potency of T cell-mediated lysis by BiTE antibodies specific for a large melanoma surface antigen

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Mode of cytotoxic action of T cell-engaging BiTE antibody MT110.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

In situ analysis of the antigen-processing machinery in acute myeloid leukaemic blasts by tissue microarray

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Impaired antigen presentation in neoplasia: basic mechanisms and implications for acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Age-related risk profile and chemotherapy dose response in acute myeloid leukemia: a study by the German Acute Myeloid Leukemia Cooperative Group

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Acute myeloid leukaemia in the elderly: a review

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Monocyte enrichment from leukapharesis products for the generation of DCs by plastic adherence, or by positive or negative selection

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Functional characterization of T lymphocytes derived from patients with acute myelogenous leukemia and chemotherapy-induced leukopenia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

High CD33 expression levels in acute myeloid leukemia cells carrying the nucleophosmin (NPM1) mutation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Influence of CD33 expression levels and ITIM-dependent internalization on gemtuzumab ozogamicin-induced cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Strictly target cell-dependent activation of T cells by bispecific single-chain antibody constructs of the BiTE class

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

A novel CD19-directed recombinant bispecific antibody derivative with enhanced immune effector functions for human leukemic cells.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

CD19-/CD3-bispecific antibody of the BiTE class is far superior to tandem diabody with respect to redirected tumor cell lysis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Bispecific antibodies engage T cells for antitumor immunotherapy

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

A single-chain triplebody with specificity for CD19 and CD33 mediates effective lysis of mixed lineage leukemia cells by dual targeting.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

21 January 2018

Expression of the target receptor CD33 in CD34+/CD38-/CD123+ AML stem cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

7 January 2021

based on heuristic

inferred from DOI database lookup

A recombinant trispecific single-chain Fv derivative directed against CD123 and CD33 mediates effective elimination of acute myeloid leukaemia cells by dual targeting

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

7 January 2021

based on heuristic

inferred from DOI database lookup

Complete remission after blinatumomab-induced donor T-cell activation in three pediatric patients with post-transplant relapsed acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

7 January 2021

based on heuristic

inferred from DOI database lookup

Circulating T cells in patients with untreated acute myelogenous leukemia are heterogeneous and can be activated through the CD3/TCR complex

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

7 January 2021

based on heuristic

inferred from DOI database lookup

Differences in CD33 intensity between various myeloid neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

7 January 2021

based on heuristic

inferred from DOI database lookup

Simultaneous engagement of the activatory receptors NKG2D and CD3 for retargeting of effector cells to CD33-positive malignant cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.341

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/LEU.2012.341

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23178753%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23178753%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

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