(Q44140093)

30 November 2017

title

Effect of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on endothelial cell growth, differentiation and apoptosis (English)

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30 November 2017

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Yoon Lee

1

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30 November 2017

Hyun-Kyung Kim

2

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30 November 2017

Hyo-Eun Park

3

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30 November 2017

Myung Hee Park

4

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30 November 2017

Young Ae Joe

5

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30 November 2017

language of work or name

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1 August 2002

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Molecular and Cellular Biochemistry

30 November 2017

published in

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30 November 2017

volume

237

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30 November 2017

issue

1-2

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30 November 2017

page(s)

69-76

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A single amino acid substitution in yeast eIF-5A results in mRNA stabilization

30 November 2017

cites work

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12 December 2020

Changes in eIF-4D hypusine modification or abundance are not correlated with translational repression in HeLa cells

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12 December 2020

Rapid induction of apoptosis by deregulated uptake of polyamine analogues

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12 December 2020

Effects of inhibitors of deoxyhypusine synthase on the differentiation of mouse neuroblastoma and erythroleukemia cells

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12 December 2020

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

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12 December 2020

Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

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12 December 2020

Deoxyhypusine synthase gene is essential for cell viability in the yeast Saccharomyces cerevisiae

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12 December 2020

Biochemistry and function of hypusine formation on eukaryotic initiation factor 5A.

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12 December 2020

Identification of hypusine, an unusual amino acid, in a protein from human lymphocytes and of spermidine as its biosynthetic precursor

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12 December 2020

The HYP2 gene of Saccharomyces cerevisiae is essential for aerobic growth: characterization of different isoforms of the hypusine-containing protein Hyp2p and analysis of gene disruption mutants

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12 December 2020

Post-translational modification of the protein-synthesis initiation factor eIF-4D by spermidine in rat hepatoma cells

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12 December 2020

Hypusine: its post-translational formation in eukaryotic initiation factor 5A and its potential role in cellular regulation.

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12 December 2020

Detection of a sub-set of polysomal mRNAs associated with modulation of hypusine formation at the G1-S boundary. Proposal of a role for eIF-5A in onset of DNA replication

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12 December 2020

Deoxyhypusine hydroxylase from rat testis. Partial purification and characterization

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12 December 2020

Regulation of biosynthesis of hypusine in Chinese hamster ovary cells. Evidence for eIF-4D precursor polypeptides.

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12 December 2020

Purification and characterization of protein synthesis initiation factors eIF-1, eIF-4C, eIF-4D, and eIF-5 from rabbit reticulocytes

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12 December 2020

Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation

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12 December 2020

Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines.

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12 December 2020

Models of in vitro angiogenesis: endothelial cell differentiation on fibrin but not matrigel is transcriptionally dependent

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12 December 2020

Inhibition of the G1-S transition of the cell cycle by inhibitors of deoxyhypusine hydroxylation

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12 December 2020

Apoptosis of vascular endothelial cells by fibroblast growth factor deprivation

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12 December 2020

Hypusine formation in protein by a two-step process in cell lysates

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12 December 2020

Protein synthesis initiation factor eIF-4D. Functional comparison of native and unhypusinated forms of the protein

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12 December 2020

Diamine and Triamine Analogs and Derivatives as Inhibitors of Deoxyhypusine Synthase: Synthesis and Biological Activity

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12 December 2020

Effect of initiation factor eIF-5A depletion on protein synthesis and proliferation of Saccharomyces cerevisiae

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12 December 2020

Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine may be due to hypusine depletion

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12 December 2020

Cell-free synthesis of deoxyhypusine. Separation of protein substrate and enzyme and identification of 1,3-diaminopropane as a product of spermidine cleavage.

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12 December 2020

Effects of N1-guanyl-1,7-diaminoheptane, an inhibitor of deoxyhypusine synthase, on the growth of tumorigenic cell lines in culture

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12 December 2020

Excess putrescine accumulation inhibits the formation of modified eukaryotic initiation factor 5A (eIF-5A) and induces apoptosis

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12 December 2020

Effects of translation initiation factor eIF-5A on the functioning of human T-cell leukemia virus type I Rex and human immunodeficiency virus Rev inhibited trans dominantly by a Rex mutant deficient in RNA binding

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12 December 2020

Features of the spermidine-binding site of deoxyhypusine synthase as derived from inhibition studies. Effective inhibition by bis- and mono-guanylated diamines and polyamines.

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12 December 2020

Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae

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12 December 2020

The essential role of hypusine in eukaryotic translation initiation factor 4D (eIF-4D). Purification of eIF-4D and its precursors and comparison of their activities

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12 December 2020

Hypusine is essential for eukaryotic cell proliferation.

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12 December 2020

Deoxyhypusine synthase activity is essential for cell viability in the yeast Saccharomyces cerevisiae

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12 December 2020

Identifiers

DOI

10.1023/A:1016535217038

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Dimensions Publication ID

30 November 2017

1026747023

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