(Q44145918)

30 November 2017

title

MEKK1-induced apoptosis requires TRAIL death receptor activation and is inhibited by AKT/PKB through inhibition of MEKK1 cleavage (English)

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30 November 2017

Andrea H Bild

1

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30 November 2017

Francisco J Mendoza

2

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30 November 2017

Erika M Gibson

3

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30 November 2017

Mei Huang

4

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30 November 2017

Jacylyn Villanueva

5

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30 November 2017

Timothy P Garrington

6

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30 November 2017

Richard Jove

7

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30 November 2017

Gary L Johnson

8

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30 November 2017

Spencer B Gibson

9

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30 November 2017

language of work or name

English

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publication date

1 September 2002

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30 November 2017

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30 November 2017

volume

21

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30 November 2017

issue

43

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30 November 2017

page(s)

6649-6656

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205819

30 November 2017

exact match

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cites work

Apoptosis control by death and decoy receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Apoptotic pathways: paper wraps stone blunts scissors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Mutations in apoptosis genes: a pathogenetic factor for human disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

The receptor for the cytotoxic ligand TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Protein kinase G activates the JNK1 pathway via phosphorylation of MEKK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

21 January 2018

1 reference

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Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

21 January 2018

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Akt is more than just a Bad kinase

21 January 2018

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Impaired Fas response and autoimmunity in Pten+/- mice

21 January 2018

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7 January 2021

TRAIL: a molecule with multiple receptors and control mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

7 January 2021

How TRAIL kills cancer cells, but not normal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

7 January 2021

Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

1 reference

7 January 2021

Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

7 January 2021

Inhibition of fas death signals by FLIPs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205819

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205819

1 reference

30 November 2017

1 reference