(Q44182059)

30 November 2017

Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species (English)

1 reference

30 November 2017

Victoria I Bunik

1

1 reference

PubMed ID

12383259

30 November 2017

Christian Sievers

series ordinal

2

1 reference

PubMed ID

12383259

30 November 2017

language of work or name

English

0 references

publication date

1 October 2002

1 reference

30 November 2017

1 reference

30 November 2017

269

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30 November 2017

20

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30 November 2017

5004-5015

1 reference

Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes

30 November 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

The pyruvate dehydrogenase multi-enzyme complex from Gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Domains, motifs, and linkers in 2-oxo acid dehydrogenase multienzyme complexes: a paradigm in the design of a multifunctional protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Rapid intramolecular coupling of active sites in the pyruvate dehydrogenase complex of Escherichia coli : Mechanism for rate enhancement in a multimeric structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Elementary steps in the reaction mechanism of the pyruvate dehydrogenase multienzyme complex from Escherichia coli: kinetics of acetylation and deacetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Intermediates in the catalytic action of lipoyl dehydrogenase (diaphorase)

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Crystal structure of the free radical intermediate of pyruvate:ferredoxin oxidoreductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

The production of superoxide anion radicals in the reaction of reduced flavins and flavoproteins with molecular oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Contribution of different enzymes to flavoprotein fluorescence of isolated rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Reactive oxygen species as cellular messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Mitochondria in the programmed death phenomena; a principle of biology: "it is better to die than to be wrong".

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Reactive oxygen species-mediated inactivation of pyruvate dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Inactivation of aconitase and oxoglutarate dehydrogenase in skeletal muscle in vitro by superoxide anions and/or nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Mitochondrial stress protein recognition of inactivated dehydrogenases during mammalian cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Reduced Activities of Thiamine-Dependent Enzymes in the Brains and Peripheral Tissues of Patients With Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Brain protein and alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

A computer model analysis of the active-site coupling mechanism in the pyruvate dehydrogenase multienzyme complex of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Acyl group and electron pair relay system: A network of interacting lipoyl moieties in the pyruvate and α-ketoglutarate dehydrogenase complexes from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Lipoic and dihydrolipoic acids as antioxidants. A critical evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

alpha-Lipoic acid as a biological antioxidant

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

The pharmacology of the antioxidant lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Interaction of thioredoxins with target proteins: role of particular structural elements and electrostatic properties of thioredoxins in their interplay with 2-oxoacid dehydrogenase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Purification of 2-oxo acid dehydrogenase multienzyme complexes from ox heart by a new method

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Kinetic analysis of the role of lipoic acid residues in the pyruvate dehydrogenase multienzyme complex of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Biochemical characterization of lucigenin (Bis-N-methylacridinium) as a chemiluminescent probe for detecting intramitochondrial superoxide anion radical production

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

The mechanism of the quinone reductase reaction of pig heart lipoamide dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

A method for the detection of superoxide in biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Spin-label study of the mobility of enzyme-bound lipoic acid in the pyruvate dehydrogenase multienzyme complex of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Intermediates in reductive transacetylation catalyzed by pyruvate dehydrogenase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Molecular aspects of the removal of ferritin-bound iron by DL-dihydrolipoate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

On the mechanism of the chromate reduction by glutathione: ESR evidence for the glutathionyl radical and an isolable Cr(V) intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Redox Properties of Protein Disulfide Bond in Oxidized Thioredoxin and Lysozyme: A Pulse Radiolysis Study†

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

The cytotoxic lipid peroxidation product, 4-hydroxy-2-nonenal, specifically inhibits decarboxylating dehydrogenases in the matrix of plant mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Elementary steps in the reaction mechanism of the alpha-ketoglutarate dehydrogenase multienzyme complex from Escherichia coli: kinetics of succinylation and desuccinylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Magnetic circular dichroism studies on the active-site flavin of lipoamide dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Mechanism of the Clostridium thermoaceticum pyruvate:ferredoxin oxidoreductase: evidence for the common catalytic intermediacy of the hydroxyethylthiamine pyropyrosphate radical

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Reactions of oxidizing and reducing radical probes with lipoamide dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Direct demonstration of superoxide anion production during the oxidation of reduced flavin and of its catalytic decomposition by erythrocuprein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Inactivation of 2-oxoglutarate dehydrogenase in rat liver mitochondria by its substrate and t-butyl hydroperoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Inhibition of select mitochondrial enzymes in PC12 cells exposed to S-(1,1,2,2-tetrafluoroethyl)-L-cysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Thiamine-dependent enzyme changes in the brains of alcoholics: relationship to the Wernicke-Korsakoff syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Thioredoxin reduction dependent on alpha-ketoacid oxidation by alpha-ketoacid dehydrogenase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Using lipoate enantiomers and thioredoxin to study the mechanism of the 2-oxoacid-dependent dihydrolipoate production by the 2-oxoacid dehydrogenase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Phenoxyl radical-induced thiol-dependent generation of reactive oxygen species: implications for benzene toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Dihydrolipoamide-mediated redox cycling of quinones

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Quantification of superoxide radical formation in intact vascular tissue using a Cypridina luciferin analog as an alternative to lucigenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Reduction of aryl-nitroso compounds by pyridine and flavin coenzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Symmetry and asymmetry of the pyruvate dehydrogenase complexes from Azotobacter vinelandii and Escherichia coli as reflected by fluorescence and spin-label studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Spin labeling of protein sulfhydryl groups by spin trapping a sulfur radical: Application to bovine serum albumin and myosin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Peroxynitrite-mediated oxidation of albumin to the protein-thiyl free radical

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

The interaction between lipoamide dehydrogenase and the peripheral-component-binding domain from the Azotobacter vinelandii pyruvate dehydrogenase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Sulfur-centered free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Superoxide generation by the respiratory chain of tumor mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Mitochondrial aconitase is a source of hydroxyl radical. An electron spin resonance investigation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Spin trapping the cysteine thiyl radical with phenyl-N-t-butylnitrone

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

ESR and HPLC-EC analysis of the interaction of hydroxyl radical with DMSO: rapid reduction and quantification of POBN and PBN nitroxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Thiyl radicals--formation during peroxidase-catalyzed metabolism of acetaminophen in the presence of thiols

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Thiyl free radical metabolites of thiol drugs, glutathione, and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Thiyl free radical production with hematoporphyrin derivative, cysteine and light: a spin-trapping study

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

The production of free radicals during the autoxidation of cysteine and their effect on isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

Evidence against the generation of free hydroxyl radicals from the interaction of copper,zinc-superoxide dismutase and hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.03204.X

10.1046/J.1432-1033.2002.03204.X

21 January 2018

Identifiers

DOI

1 reference

30 November 2017

1 reference

PubMed ID

12383259