(Q44193814)

30 November 2017

title

Activation of initiator caspases through a stable dimeric intermediate (English)

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30 November 2017

Min Chen

1

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30 November 2017

Aaron Orozco

series ordinal

2

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30 November 2017

David M Spencer

series ordinal

3

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30 November 2017

Jin Wang

series ordinal

4

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30 November 2017

language of work or name

English

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publication date

23 October 2002

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Journal of Biological Chemistry

30 November 2017

published in

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30 November 2017

volume

277

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30 November 2017

issue

52

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30 November 2017

page(s)

50761-50767

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Mammalian cell death proteases: a family of highly conserved aspartate specific cysteine proteases

30 November 2017

cites work

1 reference

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

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Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

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Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling

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Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

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Caspase-10 is an initiator caspase in death receptor signaling

21 January 2018

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Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

21 January 2018

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21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Structural basis for the activation of human procaspase-7

21 January 2018

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Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

21 January 2018

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Dimer formation drives the activation of the cell death protease caspase 9

21 January 2018

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Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity

21 January 2018

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21 January 2018

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Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

21 January 2018

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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

21 January 2018

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Improved artificial death switches based on caspases and FADD.

21 January 2018

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Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide

21 January 2018

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Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding

21 January 2018

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Role of GTP hydrolysis in fission of caveolae directly from plasma membranes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M210356200

1 reference

30 November 2017

1 reference