(Q44222492)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12441342%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

title

A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (PPARalpha ) versus liver X receptor (English)

1 reference

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15 December 2019

13

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15 December 2019

author name string

Jeffrey Thomas

1

1 reference

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15 December 2019

Kelli S Bramlett

2

1 reference

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15 December 2019

Chahrzad Montrose

3

1 reference

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15 December 2019

Patricia Foxworthy

4

1 reference

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15 December 2019

Patrick I Eacho

5

1 reference

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15 December 2019

Denis McCann

6

1 reference

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15 December 2019

Guoqing Cao

7

1 reference

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15 December 2019

Anton Kiefer

8

1 reference

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15 December 2019

Jeff McCowan

9

1 reference

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15 December 2019

Kuo-Long Yu

10

1 reference

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15 December 2019

Timothy Grese

11

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15 December 2019

William W Chin

12

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15 December 2019

Laura F Michael

14

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15 December 2019

language of work or name

English

0 references

publication date

18 November 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12441342%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

15 December 2019

published in

1 reference

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15 December 2019

volume

278

1 reference

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15 December 2019

issue

4

1 reference

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15 December 2019

page(s)

2403-2410

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Mechanism of action of fibrates on lipid and lipoprotein metabolism

15 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Regulation of the peroxisomal beta-oxidation-dependent pathway by peroxisome proliferator-activated receptor alpha and kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Role of LXRs in control of lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Design and synthesis of 2-methyl-2-[4-(2-[5-methyl-2-aryloxazol-4-yl]ethoxy)phenoxy]propionic acids: a new class of dual PPARalpha/gamma agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Effects of selective estrogen receptor modulators (SERMs) on coactivator nuclear receptor (NR) box binding to estrogen receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Plasma cholesterol concentration and mortality. The Whitehall Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Cross-talk between fatty acid and cholesterol metabolism mediated by liver X receptor-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Molecular determinants for the tissue specificity of SERMs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

The role of fibric acids in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200

Fatty acid regulation of liver X receptors (LXR) and peroxisome proliferator-activated receptor alpha (PPARalpha ) in HEK293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209629200