(Q44257111)

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The selective A2A receptor antagonist SCH 58261 reduces striatal transmitter outflow, turning behavior and ischemic brain damage induced by permanent focal ischemia in the rat.

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16 December 2019

The selective A2A receptor antagonist SCH 58261 reduces striatal transmitter outflow, turning behavior and ischemic brain damage induced by permanent focal ischemia in the rat (English)

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16 December 2019

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16 December 2019

Rosalia Bertorelli

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16 December 2019

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Leonardo Pantoni

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16 December 2019

Francesca Bordoni

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16 December 2019

Marco Gianfriddo

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16 December 2019

Loria Bianchi

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16 December 2019

Maria Giuliana Vannucchi

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16 December 2019

Angela Monopoli

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16 December 2019

Felicita Pedata

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16 December 2019

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16 December 2019

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16 December 2019

959

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16 December 2019

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16 December 2019

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16 December 2019

Simultaneous determination of basal and evoked output levels of aspartate, glutamate, taurine and 4-aminobutyric acid during microdialysis and from superfused brain slices.

1 reference

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Neonatal cerebral hypoxia-ischemia: the effect of adenosine receptor antagonists.

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A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice

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The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death

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Striatal A2A adenosine receptor antagonism differentially modifies striatal glutamate outflow in vivo in young and aged rats

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Effects of adenosine derivatives on human and rabbit platelet aggregation. Correlation of adenosine receptor affinities and antiaggregatory activity

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Pathobiology of ischaemic stroke: an integrated view

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Tissue distribution of adenosine receptor mRNAs in the rat.

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Cyclooxygenase-2 expression in rat microglia is induced by adenosine A2a-receptors

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CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil.

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7 January 2021

Neuronal necrosis after middle cerebral artery occlusion in Wistar rats progresses at different time intervals in the caudoputamen and the cortex

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Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation

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7 January 2021

Acetylcholine release from the frontal cortex during exploratory activity.

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Cortical neuronal function during ischemia. Effects of occlusion of one middle cerebral artery on single-unit activity in cats

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7 January 2021

Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis.

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7 January 2021

Functional assessments in mice and rats after focal stroke

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7 January 2021

Protection against hippocampal kainate excitotoxicity by intracerebral administration of an adenosine A2A receptor antagonist.

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7 January 2021

Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists.

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7 January 2021

Adenosine in the central nervous system: release mechanisms and extracellular concentrations

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7 January 2021

Reversible middle cerebral artery occlusion without craniectomy in rats

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7 January 2021

Effect of ischemic cerebral volume changes on behavior

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7 January 2021

Flow thresholds for extracellular purine catabolite elevation in cat focal ischemia

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7 January 2021

Striatal outflow of adenosine, excitatory amino acids, gamma-aminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion: correlations with neurological deficit and histopathological damage

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7 January 2021

Blockade of adenosine A2A receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats

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7 January 2021

Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion

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7 January 2021

Taurine as osmoregulator and neuromodulator in the brain

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7 January 2021

Modulation of extracellular neurotransmitter levels in the nucleus accumbens by a taurine uptake inhibitor

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7 January 2021

Interaction between striatal excitatory amino acid and gamma-aminobutyric acid (GABA) receptors in the turning behaviour of rats

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7 January 2021

Protective effect of the glutamate antagonist, MK-801 in focal cerebral ischemia in the cat.

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7 January 2021

The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat

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7 January 2021

Adenosine extracellular brain concentrations and role of A2A receptors in ischemia.

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7 January 2021

Blockade of A(2A) adenosine receptors leads to c-fos inhibition in a rat model of brain ischemia

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7 January 2021

Amino acid and purine release in rat brain following temporary middle cerebral artery occlusion

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Blockade of A2aAdenosine Receptors Positively Modulates Turning Behaviour and c-Fos Expression Induced by D1Agonists in Dopamine-denervated Rats

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7 January 2021

SCH 58261 (an adenosine A(2A) receptor antagonist) reduces, only at low doses, K(+)-evoked glutamate release in the striatum

1 reference

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7 January 2021

Adenosine A2A receptor stimulation enhances striatal extracellular glutamate levels in rats

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Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum.

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7 January 2021

Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines

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7 January 2021

Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists

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Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors

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Evidence that A(2a) and not A(2b) purinoceptors are coupled to production of nitric oxide in the central regulation of blood pressure

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Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens

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7 January 2021

Changes in amino acid neurotransmitters and cerebral blood flow in the ischemic penumbral region following middle cerebral artery occlusion in the rat: correlation with histopathology

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Adenosine and cerebral ischemia: therapeutic future or death of a brave concept?

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Identifiers

10.1016/S0006-8993(02)03753-8

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12493612%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12493612%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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