(Q44264337)

1 December 2017

Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties (English)

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1 December 2017

2

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1 December 2017

4

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1 December 2017

Joan L Buss

1

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1 December 2017

Nina Gellert

series ordinal

3

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1 December 2017

Prem Ponka

series ordinal

5

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1 December 2017

language of work or name

English

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publication date

1 January 2003

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1 December 2017

Biochemical Pharmacology

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1 December 2017

65

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1 December 2017

2

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1 December 2017

161-172

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Iron chelators induce apoptosis in proliferating cells

1 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Apoptosis during iron chelator-induced differentiation in F9 embryonal carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Desferrioxamine enhances the effects of gamma radiation on clonogenic survival and the formation of chromosomal aberrations in endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Pyridoxal isonicotinoyl hydrazone. Effective iron chelation after oral administration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Biliary iron excretion in rats following pyridoxal isonicotinoyl hydrazone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Toxicological Study of Pyridoxal Isonicotinoyl Hydrazone: Acute and Subchronic Toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Effect of pyridoxal isonicotinoyl hydrazone and other hydrazones on iron release from macrophages, reticulocytes and hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

A study of the mechanism of action of pyridoxal isonicotinoyl hydrazone at the cellular level using reticulocytes loaded with non-heme 59Fe

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

α-Tocopheryl succinate-induced apoptosis in Jurkat T cells involves caspase-3 activation, and both lysosomal and mitochondrial destabilisation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Induction of cancer cell apoptosis by alpha-tocopheryl succinate: molecular pathways and structural requirements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Inhibition of inflammatory endothelial responses by a pathway involving caspase activation and p65 cleavage.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

The effect of various chelating agents on the mobilization of iron from reticulocytes in the presence and absence of pyridoxal isonicotinoyl hydrazone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Mobilization of intracellular iron by analogs of pyridoxal isonicotinoyl hydrazone (PIH) is determined by the membrane permeability of the iron-chelator complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Induction of cell death by the lysosomotropic detergent MSDH.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Molecular characterization of mitochondrial apoptosis-inducing factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Evidence that transferrin supports cell proliferation by supplying iron for DNA synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Ferric pyridoxal isonicotinoyl hydrazone can provide iron for heme synthesis in reticulocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

The biochemistry of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Regulation of growth of cultured hepatic epithelial cells by transferrin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Replacement of transferrin in serum-free cultures of mitogen-stimulated mouse lymphocytes by a lipophilic iron chelator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Crystal and molecular structure of 2-hydroxy-1-naphthaldehyde isonicotinoyl hydrazone (NIH) and its iron(III) complex: an iron chelator with anti-tumour activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Uptake and intracellular handling of iron from transferrin and iron chelates by mitogen stimulated mouse lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Iron chelators of the pyridoxal isonicotinoyl hydrazone class. Relationship of the lipophilicity of the apochelator to its ability to mobilize iron from reticulocytes in vitro: reappraisal of reported partition coefficients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

Iron chelators of the pyridoxal isonicotinoyl hydrazone class. Relationship of the lipophilicity of the apochelator to its ability to mobilise iron from reticulocytes in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901512-5

10.1016/S0006-2952(02)01512-5

7 January 2021

Identifiers

DOI

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1 December 2017

1 reference