(Q44268134)

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SM-31900, a novel NMDA receptor glycine-binding site antagonist, reduces infarct volume induced by permanent middle cerebral artery occlusion in spontaneously hypertensive rats

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

SM-31900, a novel NMDA receptor glycine-binding site antagonist, reduces infarct volume induced by permanent middle cerebral artery occlusion in spontaneously hypertensive rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

cerebral artery occlusion

1 reference

based on heuristic

inferred from title

middle cerebral artery occlusion

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based on heuristic

inferred from title

14 December 2021

author name string

Ken-ichi Ohtani

1

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Hiroyasu Tanaka

2

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Yukihiro Ohno

3

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

publication date

1 April 2003

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Neurochemistry International

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

42

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

375-384

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Dose escalation study of the NMDA glycine-site antagonist licostinel in acute ischemic stroke.

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Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient global ischemia in the rabbit brain

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The glycine antagonist GV150526 protects somatosensory evoked potentials and reduces the infarct area in the MCAo model of focal ischemia in the rat.

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The neuroprotective glycine receptor antagonist GV150526 does not produce neuronal vacuolization or cognitive deficits in rats

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Focal Brain Ischemia in the Rat: Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries

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The effect of the NMDA receptor antagonist MK-801 on cerebral blood flow and infarct volume in experimental focal stroke

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Progression of ischaemic stroke and excitotoxic aminoacids

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Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage

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Calcium: still center-stage in hypoxic-ischemic neuronal death

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The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death

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Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists

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Cloning and characterization of chi-1: a developmentally regulated member of a novel class of the ionotropic glutamate receptor family

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Different susceptibilities to cerebral infarction in spontaneously hypertensive (SHR) and normotensive Sprague-Dawley rats

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Pre- and post-treatment with MK-801 but not pretreatment alone reduces neocortical damage after focal cerebral ischemia in the rat.

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The quantification of cerebral infarction following focal ischemia in the rat: influence of strain, arterial pressure, blood glucose concentration, and age.

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Safety and tolerability of GV150526 (a glycine site antagonist at the N-methyl-D-aspartate receptor) in patients with acute stroke

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Neuronal vacuolization and necrosis induced by the noncompetitive N-methyl-D-aspartate (NMDA) antagonist MK(+)801 (dizocilpine maleate): a light and electron microscopic evaluation of the rat retrosplenial cortex

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Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil.

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Rodent models of cerebral ischemia

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Excitotoxic index — a biochemical marker of selective vulnerability

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Safety and tolerability of the glutamate antagonist CGS 19755 (Selfotel) in patients with acute ischemic stroke. Results of a phase IIa randomized trial

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Lack of effect of L-687,414 ((+)-cis-4-methyl-HA-966), an NMDA receptor antagonist acting at the glycine site, on cerebral glucose metabolism and cortical neuronal morphology

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Competitive as well as uncompetitive N-methyl-D-aspartate receptor antagonists affect cortical neuronal morphology and cerebral glucose metabolism

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The N-methyl-D-aspartate (NMDA) receptor glycine site antagonist ACEA 1021 does not produce pathological changes in rat brain

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Glycine potentiates the NMDA response in cultured mouse brain neurons

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Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes

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ACEA 1021, a glycine site antagonist with minor psychotomimetic and amnestic effects in rats.

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Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition

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Glycine antagonist (gavestinel) in neuroprotection (GAIN International) in patients with acute stroke: a randomised controlled trial. GAIN International Investigators

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Identification of 3,5-dihydro-2-aryl-1H-pyrazolo[3,4-c]quinoline-1,4(2H)-diones as novel high-affinity glycine site N-methyl-D-aspartate antagonists

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Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

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Blocking the glycine-binding site of NMDA receptors prevents the progression of ischemic pathology induced by bilateral carotid artery occlusion in spontaneously hypertensive rats

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In vitro and in vivo antagonistic activities of SM-31900 for the NMDA receptor glycine-binding site.

1 reference

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Infarct volume varies with rat strain and vendor in focal cerebral ischemia induced by transcranial middle cerebral artery occlusion

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Protective effect of the glutamate antagonist, MK-801 in focal cerebral ischemia in the cat.

1 reference

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inferred from DOI database lookup

Focal cerebral ischaemia in the cat: treatment with the glutamate antagonist MK-801 after induction of ischaemia

1 reference

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based on heuristic

inferred from DOI database lookup

The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat

1 reference

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inferred from DOI database lookup

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inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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based on heuristic

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Focal cerebral ischemia in chronic hypertension: no protection by (R)-phenylisopropyladenosine.

1 reference

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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7 January 2021

based on heuristic

inferred from DOI database lookup

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

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inferred from DOI database lookup

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7 January 2021

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inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900137-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Glycine site antagonist attenuates infarct size in experimental focal ischemia. Postmortem and diffusion mapping studies

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery Occlusion

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900137-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Failure of MK-801 to reduce infarct volume in thrombotic middle cerebral artery occlusion in rats

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Reversible middle cerebral artery occlusion without craniectomy in rats

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0197-0186(02)00137-7

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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