(Q44276649)

English

Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump

scientific article published on 13 January 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 December 2017

Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump (English)

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Europe PubMed Central

PubMed publication ID

1 December 2017

(E)-guggulsterone

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author name string

Jisong Cui

1

1 reference

Europe PubMed Central

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1 December 2017

Li Huang

2

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Europe PubMed Central

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1 December 2017

Annie Zhao

3

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Europe PubMed Central

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1 December 2017

Jane-L Lew

4

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1 December 2017

Jinghua Yu

5

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Europe PubMed Central

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1 December 2017

Soumya Sahoo

6

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Europe PubMed Central

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1 December 2017

Peter T Meinke

7

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Europe PubMed Central

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1 December 2017

Inmaculada Royo

8

1 reference

Europe PubMed Central

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1 December 2017

Fernando Pelaez

9

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1 December 2017

Samuel D Wright

10

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Europe PubMed Central

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1 December 2017

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publication date

13 January 2003

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1 December 2017

number of pages

7

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Journal of Biological Chemistry

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1 December 2017

278

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1 December 2017

12

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1 December 2017

10214-10220

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Europe PubMed Central

PubMed publication ID

1 December 2017

Ancient-modern concordance in Ayurvedic plants: some examples

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

A natural product that lowers cholesterol as an antagonist ligand for FXR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Identification of a nuclear receptor for bile acids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Bile acids: natural ligands for an orphan nuclear receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

FXR, a bile acid receptor and biological sensor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Expression and regulation of hepatic drug and bile acid transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Hepatic transport of bile salts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

The continuing importance of bile acids in liver and intestinal disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Identification of a chemical tool for the orphan nuclear receptor FXR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Identification of a nuclear receptor that is activated by farnesol metabolites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Regulation of the farnesoid X receptor (FXR) by bile acid flux in rabbits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Nuclear receptor coregulators: cellular and molecular biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Human vitamin D receptor is selectively phosphorylated by protein kinase C on serine 51, a residue crucial to its trans-activation function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Redundant pathways for negative feedback regulation of bile acid production

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209323200

21 January 2018

Identifiers

10.1074/JBC.M209323200

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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