(Q44277876)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12527324%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

title

Potent inhibition of human folylpolyglutamate synthetase by a phosphinic acid mimic of the tetrahedral reaction intermediate (English)

1 reference

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16 December 2019

4

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16 December 2019

author name string

John J McGuire

1

1 reference

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16 December 2019

William H Haile

2

1 reference

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16 December 2019

Nadya Valiaeva

3

1 reference

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16 December 2019

Jianxia Guo

5

1 reference

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16 December 2019

James K Coward

6

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16 December 2019

language of work or name

English

0 references

publication date

1 February 2003

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16 December 2019

published in

Biochemical Pharmacology

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16 December 2019

volume

65

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16 December 2019

issue

3

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16 December 2019

page(s)

315-318

1 reference

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Nomenclature and Symbolism for Amino Acids and Peptides. Recommendations 1983

16 December 2019

cites work

1 reference

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Anticancer Antifolates: Current Status and Future Directions

7 January 2021

1 reference

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Folylpolyglutamate synthetase inhibition and cytotoxic effects of methotrexate analogs containing 2,omega-diaminoalkanoic acids.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Synthesis and biological evaluation of N alpha-(4-amino-4-deoxy-10-methylpteroyl)-DL-4,4-difluoroornithine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Dihydrofolate synthetase and folylpolyglutamate synthetase: direct evidence for intervention of acyl phosphate intermediates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Design, synthesis, and biochemical evaluation of phosphonate and phosphonamidate analogs of glutathionylspermidine as inhibitors of glutathionylspermidine synthetase/amidase from Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Mechanism-based inhibition of human folylpolyglutamate synthetase: design, synthesis, and biochemical characterization of a phosphapeptide mimic of the tetrahedral intermediate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Phosphinic acid pseudopeptides analogous to glutamyl-gamma-glutamate: synthesis and coupling to pteroyl azides leads to potent inhibitors of folylpoly-gamma-glutamate synthetase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Structural specificity of inhibition of human folylpolyglutamate synthetase by ornithine-containing folate analogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Aldehyde and phosphinate analogs of glutathione and glutathionylspermidine: potent, selective binding inhibitors of the E. coli bifunctional glutathionylspermidine synthetase/amidase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Upstream organization of and multiple transcripts from the human folylpoly-gamma-glutamate synthetase gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Human cytosolic and mitochondrial folylpolyglutamate synthetase are electrophoretically distinct. Expression in antifolate-sensitive and -resistant human cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

Uptake of 5-formyltetrahydrofolate in isolated rat liver mitochondria is carrier-mediated

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901602-7

10.1016/S0006-2952(02)01602-7

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12527324%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference