(Q44283112)

English

The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.

scientific article published in January 2003

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scholarly article

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16 December 2019

The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination (English)

1 reference

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16 December 2019

Norbert Polacek

1

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16 December 2019

author name string

Maria J Gomez

2

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16 December 2019

Koichi Ito

3

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16 December 2019

Liqun Xiong

4

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16 December 2019

Yoshikazu Nakamura

5

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16 December 2019

Alexander Mankin

6

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16 December 2019

publication date

1 January 2003

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16 December 2019

1 reference

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16 December 2019

11

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16 December 2019

1

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16 December 2019

103-112

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16 December 2019

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

1 reference

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7 January 2021

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Mechanism of ribosomal peptide bond formation.

1 reference

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7 January 2021

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A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition

1 reference

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7 January 2021

based on heuristic

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23S rRNA positions essential for tRNA binding in ribosomal functional sites

1 reference

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7 January 2021

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Hydrolysis of fMet-tRNA by peptidyl transferase

1 reference

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7 January 2021

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A new beginning of the end of translation.

1 reference

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7 January 2021

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Mutations in the highly conserved GGQ motif of class 1 polypeptide release factors abolish ability of human eRF1 to trigger peptidyl-tRNA hydrolysis.

1 reference

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7 January 2021

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Reconstitution of functional 50S ribosomes from in vitro transcripts of Bacillus stearothermophilus 23S rRNA.

1 reference

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7 January 2021

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Mutations at nucleotides G2251 and U2585 of 23 S rRNA perturb the peptidyl transferase center of the ribosome

1 reference

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7 January 2021

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The accuracy of ribosomal RNA comparative structure models

1 reference

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7 January 2021

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Cloning and overexpression of polypeptide release factor 1 of Thermus thermophilus.

1 reference

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7 January 2021

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Single amino acid substitution in prokaryote polypeptide release factor 2 permits it to terminate translation at all three stop codons

1 reference

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7 January 2021

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Neurobiology: internal model visualized.

1 reference

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7 January 2021

based on heuristic

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Important contribution to catalysis of peptide bond formation by a single ionizing group within the ribosome.

1 reference

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7 January 2021

based on heuristic

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Altered ribosomal RNA genes in mitochondria from mammalian cells with chloramphenicol resistance

1 reference

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7 January 2021

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Reconstitution of functionally active Thermus aquaticus large ribosomal subunits with in vitro-transcribed rRNA.

1 reference

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7 January 2021

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Effect of antibiotics on large ribosomal subunit assembly reveals possible function of 5 S rRNA.

1 reference

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7 January 2021

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Quantitative study of interaction of deacylated tRNA with Escherichia coli ribosomes. Role of 50 S subunits in formation of the E site

1 reference

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7 January 2021

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A Sparsomycin-resistant Mutant ofHalobacterium salinariumLacks a Modification at Nucleotide U2603 in the Peptidyl Transferase Centre of 23 S rRNA

1 reference

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7 January 2021

based on heuristic

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Ribosome-Catalyzed Peptidyl Transfer. Effects of Cations and pH Value

1 reference

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7 January 2021

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The formation of N-formyl-methionyl-sRNA

1 reference

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7 January 2021

based on heuristic

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Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites

1 reference

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7 January 2021

based on heuristic

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Ribosome-catalysed reaction of puromycin with a formylmethionine-containing oligonucleotide

1 reference

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7 January 2021

based on heuristic

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Action of Sparsomycin on Ribosome-catalysed Peptidyl Transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

A single adenosine with a neutral pKa in the ribosomal peptidyl transferase center

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The structural basis of ribosome activity in peptide bond synthesis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence against stabilization of the transition state oxyanion by a pKa-perturbed RNA base in the peptidyl transferase center

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

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SPARK--a novel method to monitor ribosomal peptidyl transferase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Three tRNA binding sites on Escherichia coli ribosomes

1 reference

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7 January 2021

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A temperature-sensitive mutant of Escherichia coli that shows enhanced misreading of UAG/A and increased efficiency for some tRNA nonsense suppressors

1 reference

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7 January 2021

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Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Class-1 translation termination factors: invariant GGQ minidomain is essential for release activity and ribosome binding but not for stop codon recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Translational termination: "stop" for protein synthesis or "pause" for regulation of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The importance of highly conserved nucleotides in the binding region of chloramphenicol at the peptidyl transfer centre of Escherichia coli 23S ribosomal RNA.

1 reference

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7 January 2021

based on heuristic

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Bacterial polypeptide release factor RF2 is structurally distinct from eukaryotic eRF1

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Possible involvement of peptidyl transferase in the termination step of protein biosynthesis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Functional sites of interaction between release factor RF1 and the ribosome

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of the ribosome at 5.5 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Release of peptide promoted by the GGQ motif of class 1 release factors regulates the GTPase activity of RF3.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2802%2900825-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1097-2765(02)00825-0

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12535525%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12535525%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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