(Q44291008)

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Inherent desensitisation-preventing properties of a novel, subtype-selective AMPA receptor agonist, (S)-CPW 399, as a possible explanation for its excitotoxic action in cultured cerebellar granule cells

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Europe PubMed Central

PubMed publication ID

1 December 2017

Inherent desensitisation-preventing properties of a novel, subtype-selective AMPA receptor agonist, (S)-CPW 399, as a possible explanation for its excitotoxic action in cultured cerebellar granule cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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Ettore Novellino

6

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Europe PubMed Central

PubMed publication ID

1 December 2017

author name string

Colin Sinclair

1

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Helen Reavy

2

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Europe PubMed Central

PubMed publication ID

1 December 2017

Angus Grieve

3

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Arne Schousboe

4

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Elena Morelli

5

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Giuseppe Campiani

7

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Roger Griffiths

8

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Europe PubMed Central

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1 December 2017

publication date

1 May 2003

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Europe PubMed Central

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1 December 2017

Neurochemistry International

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Europe PubMed Central

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1 December 2017

42

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Europe PubMed Central

PubMed publication ID

1 December 2017

6

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Europe PubMed Central

PubMed publication ID

1 December 2017

499-510

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

Role of desensitization of AMPA receptors on the neuronal viability and on the [Ca2+]ichanges in cultured rat hippocampal neurons

1 reference

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Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

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N-methyl-D-aspartate promotes the survival of cerebellar granule cells in culture

1 reference

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Identification of amino acid residues in GluR1 responsible for ligand binding and desensitization.

1 reference

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7 January 2021

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

1 reference

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7 January 2021

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Ca2+ entry via AMPA/KA receptors and excitotoxicity in cultured cerebellar Purkinje cells.

1 reference

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Characterization of the 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent, and subtype-selective AMPA receptor full agonist with partial desensitization properties

1 reference

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7 January 2021

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AMPA neurotoxicity in cultured cerebellar granule neurons: mode of cell death.

1 reference

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7 January 2021

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Growth conditions differentially regulate the expression of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptor subunits in cultured neurons.

1 reference

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7 January 2021

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New developments in the molecular pharmacology of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate and kainate receptors

1 reference

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7 January 2021

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Time and concentration dependency of the toxicity of excitatory amino acids on cerebral neurones in primary culture

1 reference

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7 January 2021

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Excitatory amino acid-mediated cytotoxicity and calcium homeostasis in cultured neurons

1 reference

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7 January 2021

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Direct evidence that excitotoxicity in cultured neurons is mediated via N-methyl-D-aspartate (NMDA) as well as non-NMDA receptors

1 reference

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7 January 2021

based on heuristic

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Synaptic kainate receptors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and development analysis of a new glutamate receptor subunit isoform in cerebellum

1 reference

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7 January 2021

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Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS

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Permeation of Calcium Ions Through Non-NMDA Glutamate Channels in Retinal Bipolar Cells

1 reference

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Pharmacology of AMPA antagonists and their role in neuroprotection

1 reference

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7 January 2021

based on heuristic

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Properties of AMPA receptors expressed in rat cerebellar granule cell cultures: Ca2+ influx studies

1 reference

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7 January 2021

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inferred from DOI database lookup

Cloned glutamate receptors

1 reference

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7 January 2021

based on heuristic

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Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones

1 reference

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7 January 2021

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Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes

1 reference

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7 January 2021

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Glutamate receptor subunit expression in primary neuronal and secondary glial cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900141-9

7 January 2021

based on heuristic

inferred from DOI database lookup

AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900141-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Differences in Ca2+ permeability of AMPA-type glutamate receptor channels in neocortical neurons caused by differential GluR-B subunit expression

1 reference

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7 January 2021

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Role of GABAB receptors in intracellular Ca2+ homeostasis and possible interaction between GABAA and GABAB receptors in regulation of transmitter release in cerebellar granule neurons

1 reference

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7 January 2021

based on heuristic

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Synaptic and non-synaptic AMPA receptors permeable to calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900141-9

7 January 2021

based on heuristic

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(S)-5-fluorowillardiine-mediated neurotoxicity in cultured murine cortical neurones occurs via AMPA and kainate receptors

1 reference

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7 January 2021

based on heuristic

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Excitatory amino acids as a final common pathway for neurologic disorders.

1 reference

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7 January 2021

based on heuristic

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Ca2+ permeable AMPA/kainate channels permit rapid injurious Ca2+ entry.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900141-9

7 January 2021

based on heuristic

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Glutamate toxicity in primary cerebellar cultures from mouse brain is unaffected by changes in cGMP levels.

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Cyclothiazide treatment unmasks AMPA excitotoxicity in rat primary hippocampal cultures

1 reference

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Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging

1 reference

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7 January 2021

based on heuristic

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NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release

1 reference

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The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system

1 reference

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Rapid desensitization determines the pharmacology of glutamate neurotoxicity

1 reference

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Calcium-Mediated Mechanisms in Chemically Induced Cell Death

1 reference

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Altered glutamatergic transmission in neurological disorders: from high extracellular glutamate to excessive synaptic efficacy

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons

1 reference

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7 January 2021

based on heuristic

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Activation and desensitization of AMPA/kainate receptors by novel derivatives of willardiine

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Growth conditions differentially modulate the vulnerability of developing cerebellar granule cells to excitatory amino acids.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate and the pathophysiology of hypoxic--ischemic brain damage

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Calcium in the brain under physiological and pathological conditions

1 reference

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7 January 2021

based on heuristic

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Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1 reference

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Synthesis of chiral 1-(2'-amino-2'-carboxyethyl)-1,4-dihydro-6,7-quinoxaline-2,3-diones: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor agonists and antagonists.

1 reference

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7 January 2021

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Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Glutamate-induced increase in intracellular Ca2+ in cerebral cortex neurons is transient in immature cells but permanent in mature cells

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900141-9

7 January 2021

based on heuristic

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Ca2+-Zn2+ permeable AMPA or kainate receptors: possible key factors in selective neurodegeneration

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Complex correlation between excitatory amino acid-induced increase in the intracellular Ca2+ concentration and subsequent loss of neuronal function in individual neocortical neurons in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900141-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Willardiines differentiate agonist binding sites for kainate- versus AMPA-preferring glutamate receptors in DRG and hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-0186%2802%2900141-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents.

1 reference

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7 January 2021

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A benzodiazepine recognition site associated with the non-NMDA glutamate receptor.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0197-0186(02)00141-9

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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