(Q44298049)

1 December 2017

title

Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations (English)

1 reference

1 December 2017

J Matthew Hutzler

1

1 reference

1 December 2017

Larry C Wienkers

2

1 reference

1 December 2017

Jan L Wahlstrom

3

1 reference

1 December 2017

Timothy J Carlson

4

1 reference

1 December 2017

Timothy S Tracy

5

1 reference

1 December 2017

language of work or name

English

0 references

publication date

1 February 2003

1 reference

Archives of Biochemistry and Biophysics

1 December 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

1 December 2017

volume

410

1 reference

1 December 2017

issue

1

1 reference

1 December 2017

page(s)

16-24

1 reference

The human hepatic cytochromes P450 involved in drug metabolism

1 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Molecular recognition in cytochrome P-450: mechanism for the control of uncoupling reactions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Studies of flurbiprofen 4'-hydroxylation. Additional evidence suggesting the sole involvement of cytochrome P450 2C9.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Role of cytochrome P450 2C9 and an allelic variant in the 4'-hydroxylation of (R)- and (S)-flurbiprofen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Elucidation of distinct ligand binding sites for cytochrome P450 3A4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Activation of CYP2C9-mediated metabolism by a series of dapsone analogs: kinetics and structural requirements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Crystal structure of substrate-free Pseudomonas putida cytochrome P-450

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Stoichiometry of 7-ethoxycoumarin metabolism by cytochrome P450 2B1 wild-type and five active-site mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Hydrogen peroxide formation and stoichiometry of hydroxylation reactions catalyzed by highly purified liver microsomal cytochrome P-450

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Differential mechanisms of cytochrome P450 inhibition and activation by alpha-naphthoflavone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Roles of Cytochrome b5in the Oxidation of Testosterone and Nifedipine by Recombinant Cytochrome P450 3A4 and by Human Liver Microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

Electron shuttle between membrane-bound cytochrome P450 3A4 and b5 rules uncoupling mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

The stoichiometry of the cytochrome P-450-catalyzed metabolism of methoxyflurane and benzphetamine in the presence and absence of cytochrome b5.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0003-9861%2802%2900665-3

10.1016/S0003-9861(02)00665-3

7 January 2021

Identifiers

DOI

1 reference

1 December 2017

1 reference