(Q44316235)

1 December 2017

title

Rapidly distinguishing reversible and irreversible CYP450 inhibitors by using fluorometric kinetic analyses (English)

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1 December 2017

Z Yan

1

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1 December 2017

B Rafferty

series ordinal

2

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1 December 2017

G W Caldwell

series ordinal

3

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1 December 2017

J A Masucci

series ordinal

4

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1 December 2017

publication date

1 October 2002

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European Journal of Drug Metabolism and Pharmacokinetics

1 December 2017

published in

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1 December 2017

volume

27

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1 December 2017

issue

4

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1 December 2017

page(s)

281-287

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In vitro prediction of the terfenadine-ketoconazole pharmacokinetic interaction.

1 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF03192339

Metabolism profiling, and cytochrome P450 inhibition & induction in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03192339

Validation of higher-throughput high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry assays to conduct cytochrome P450s CYP2D6 and CYP3A4 enzyme inhibition studies in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03192339

Fluorometric screening for metabolism-based drug--drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03192339

Mechanism-based inactivation of human cytochrome P450 1A2 by furafylline: detection of a 1:1 adduct to protein and evidence for the formation of a novel imidazomethide intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03192339

Midazolam oxidation by cytochrome P450 3A4 and active-site mutants: an evaluation of multiple binding sites and of the metabolic pathway that leads to enzyme inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03192339

Inhibition of cytochromes P450 by antifungal imidazole derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03192339

Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03192339

Role of CYP3A4 in human hepatic diltiazem N-demethylation: inhibition of CYP3A4 activity by oxidized diltiazem metabolites

21 January 2018

1 reference

12 December 2020

Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450

1 reference

12 December 2020

Nonspecific binding to microsomes: impact on scale-up of in vitro intrinsic clearance to hepatic clearance as assessed through examination of warfarin, imipramine, and propranolol.

1 reference

12 December 2020

Comparison of cytochrome P-450-dependent metabolism and drug interactions of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors lovastatin and pravastatin in the liver

1 reference

12 December 2020

Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes

1 reference

12 December 2020

Drug interactions with calcium channel blockers: possible involvement of metabolite-intermediate complexation with CYP3A

1 reference

12 December 2020

Inhibition and induction of cytochrome P450 and the clinical implications

1 reference

12 December 2020

The withdrawal of mibefradil (Posicor)

1 reference

12 December 2020

Inhibition of cytochrome P-450 3A (CYP3A) in human intestinal and liver microsomes: comparison of Ki values and impact of CYP3A5 expression.

1 reference

12 December 2020

Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation

1 reference

12 December 2020

Application of higher throughput screening (HTS) inhibition assays to evaluate the interaction of antiparasitic drugs with cytochrome P450s

1 reference

12 December 2020

Mechanism-based inactivation of CYP2D6 by 5-fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine

1 reference

12 December 2020

The O-demethylation of the antidementia drug galanthamine is catalysed by cytochrome P450 2D6

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03192339

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1 December 2017

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