(Q44318970)

1 December 2017

Abnormal PI3 kinase/Akt signal pathway in vagal afferent neurons and vagus nerve of streptozotocin-diabetic rats (English)

1 reference

1 December 2017

Fang Cai

1

1 reference

PubMed ID

12591159

1 December 2017

Cinda J Helke

series ordinal

2

1 reference

PubMed ID

12591159

1 December 2017

language of work or name

1 reference

1 February 2003

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1 December 2017

Molecular Brain Research

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1 December 2017

110

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1 December 2017

2

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1 December 2017

234-244

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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

1 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

The role of endogenous nerve growth factor in human diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

In sympathetic but not sensory neurones, phosphoinositide-3 kinase is important for NGF-dependent survival and the retrograde transport of 125I-betaNGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Akt activation by growth factors is a multiple-step process: the role of the PH domain

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Cellular function of p70S6K: a role in regulating cell motility

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Impaired phosphorylation and insulin-stimulated translocation to the plasma membrane of protein kinase B/Akt in adipocytes from Type II diabetic subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Diabetes and axotomy-induced deficits in retrograde axonal transport of nerve growth factor correlate with decreased levels of p75LNTR protein in lumbar dorsal root ganglia.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Effect of nerve growth factor treatment on p75NTR gene expression in lumbar dorsal root ganglia of streptozocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Low serum levels of nerve growth factor in diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Deficits in sciatic nerve neuropeptide content coincide with a reduction in target tissue nerve growth factor messenger RNA in streptozotocin-diabetic rats: effects of insulin treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Aberrant neurofilament phosphorylation in sensory neurons of rats with diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Insulin signaling is inhibited by micromolar concentrations of H(2)O(2). Evidence for a role of H(2)O(2) in tumor necrosis factor alpha-mediated insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Axonal transport of neurotrophins by visceral afferent and efferent neurons of the vagus nerve of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Endogenous levels of nerve growth factor (NGF) are altered in experimental diabetes mellitus: a possible role for NGF in the pathogenesis of diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Axonal transport of endogenous nerve growth factor (NGF) and NGF receptor in experimental diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

The regenerative deficit of peripheral nerves in experimental diabetes: its extent, timing and possible mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Spatially and Functionally Distinct Roles of the PI3-K Effector Pathway during NGF Signaling in Sympathetic Neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Streptozotocin-induced diabetes causes metabolic changes and alterations in neurotrophin content and retrograde transport in the cervical vagus nerve

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Streptozotocin-induced diabetes reduces retrograde axonal transport in the afferent and efferent vagus nerve

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Neuregulin signaling through a PI3K/Akt/Bad pathway in Schwann cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Nerve function and regeneration in diabetic and galactosaemic rats: antioxidant and metal chelator effects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Regenerating sensory neurones of diabetic rats express reduced levels of mRNA for GAP-43, gamma-preprotachykinin and the nerve growth factor receptors, trkA and p75NGFR.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Axonal regulation of Schwann cell proliferation and survival and the initial events of myelination requires PI 3-kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Impaired muscle glycogen synthase in type 2 diabetes is associated with diminished phosphatidylinositol 3-kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Inhibitory effect of hyperglycemia on insulin-induced Akt/protein kinase B activation in skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Signalling events regulating the retrograde axonal transport of 125I-beta nerve growth factor in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Impaired glucose transport and protein kinase B activation by insulin, but not okadaic acid, in adipocytes from subjects with Type II diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Insulin-like growth factor-I prevents apoptosis in sympathetic neurons exposed to high glucose

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Neurons undergo apoptosis in animal and cell culture models of diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Diabetic peripheral neuropathy: evidence for apoptosis and associated mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Regulation of vascular endothelial growth factor expression by advanced glycation end products

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Nerve growth factor-induced PKB/Akt activity is sustained by phosphoinositide 3-kinase dependent and independent signals in sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Diabetes and advanced glycation endproducts

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Phosphatidylinositol 3-kinase activity in murine motoneuron disease: the progressive motor neuropathy mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Engagement of the insulin-sensitive pathway in the stimulation of glucose transport by alpha-lipoic acid in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

Presence and localization of neurotrophin receptor tyrosine kinase (TrkA, TrkB, TrkC) mRNAs in visceral afferent neurons of the nodose and petrosal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900652-6

7 January 2021

10.1016/S0169-328X(02)00652-6

Identifiers

DOI

1 reference

1 December 2017

1 reference

PubMed ID

12591159