(Q44318983)

1 December 2017

title

Thyroid hormone receptors: lessons from knockout and knock-in mutant mice (English)

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1 December 2017

Frédéric Flamant

1

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1 December 2017

Jacques Samarut

series ordinal

2

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1 December 2017

publication date

1 March 2003

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Trends in Endocrinology and Metabolism

1 December 2017

published in

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1 December 2017

volume

14

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1 December 2017

issue

2

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1 December 2017

page(s)

85-90

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Physiological and molecular basis of thyroid hormone action

1 December 2017

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7 January 2021

How many nuclear hormone receptors are there in the human genome?

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7 January 2021

Cloning and characterization of two novel thyroid hormone receptor beta isoforms

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7 January 2021

A variant form of the nuclear triiodothyronine receptor c-ErbAalpha1 plays a direct role in regulation of mitochondrial RNA synthesis

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7 January 2021

Multiple sequences encoding potential thyroid hormone receptors isolated from mouse skeletal muscle cDNA libraries

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7 January 2021

Involvement of T3Ralpha- and beta-receptor subtypes in mediation of T3 functions during postnatal murine intestinal development

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7 January 2021

TR(beta)1 protein is preferentially expressed in the pericentral zone of rat liver and exhibits marked diurnal variation

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7 January 2021

Ablation of TRalpha2 and a concomitant overexpression of alpha1 yields a mixed hypo- and hyperthyroid phenotype in mice.

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7 January 2021

Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1

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7 January 2021

The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production

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7 January 2021

Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development

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7 January 2021

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

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7 January 2021

Resistance to thyroid hormone

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7 January 2021

An unliganded thyroid hormone receptor causes severe neurological dysfunction

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7 January 2021

Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone

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7 January 2021

A targeted dominant negative mutation of the thyroid hormone alpha 1 receptor causes increased mortality, infertility, and dwarfism in mice

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7 January 2021

Brain glucose utilization in mice with a targeted mutation in the thyroid hormone alpha or beta receptor gene

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7 January 2021

Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1

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7 January 2021

Neurodevelopmental control by thyroid hormone receptors

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7 January 2021

Functions of thyroid hormone receptors in mice

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7 January 2021

Tissue-specific actions of thyroid hormone: insights from animal models

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7 January 2021

Follicular cells of the thyroid gland require Pax8 gene function

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7 January 2021

Hypothyroidism prolongs mitotic activity in the post-natal mouse brain

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7 January 2021

Role of Thyroid Hormone Receptors in Timing Oligodendrocyte Differentiation

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7 January 2021

Deletion of the thyroid hormone receptor alpha 1 prevents the structural alterations of the cerebellum induced by hypothyroidism

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7 January 2021

Molecular mechanisms of thyroid hormone effects on bone growth and function

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7 January 2021

Functional interference between thyroid hormone receptor alpha (TRalpha) and natural truncated TRDeltaalpha isoforms in the control of intestine development.

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7 January 2021

Thyroid hormone receptor beta is essential for development of auditory function

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7 January 2021

Thyroid hormone receptor beta-dependent expression of a potassium conductance in inner hair cells at the onset of hearing

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7 January 2021

A thyroid hormone receptor that is required for the development of green cone photoreceptors

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7 January 2021

Divergent roles for thyroid hormone receptor beta isoforms in the endocrine axis and auditory system

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7 January 2021

The two thyroid hormone receptor genes have opposite effects on estrogen-stimulated sex behaviors

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7 January 2021

Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor

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7 January 2021

Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation

1 reference

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7 January 2021

Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors

1 reference

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7 January 2021

Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RAR beta 2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts

1 reference

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7 January 2021

Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice

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7 January 2021

Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene

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7 January 2021

Suppression of the deafness and thyroid dysfunction in Thrb-null mice by an independent mutation in the Thra thyroid hormone receptor alpha gene

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7 January 2021

Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus

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7 January 2021

Thyroxine promotes association of mitogen-activated protein kinase and nuclear thyroid hormone receptor (TR) and causes serine phosphorylation of TR.

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7 January 2021

The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor

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7 January 2021

Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors

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7 January 2021

Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone

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7 January 2021

Phosphorylation stimulates the transcriptional activity of the human beta 1 thyroid hormone nuclear receptor

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7 January 2021

Thyroid hormone receptor is a negative regulator in p53-mediated signaling pathways

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7 January 2021

Thyroid hormone receptor-alpha inhibits retinoic acid-responsive gene expression and modulates retinoic acid-stimulated neural differentiation in mouse embryonic stem cells

1 reference

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7 January 2021

Thyroid function and effect of aging in combined hetero/homozygous mice deficient in thyroid hormone receptors alpha and beta genes

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7 January 2021

Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency

1 reference

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7 January 2021

Effects of T3R 1 and T3R 2 Gene Deletion on T and B Lymphocyte Development

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7 January 2021

Inducible gene targeting in mice using the Cre/lox system

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7 January 2021

Thyroid hormone-independent interaction between the thyroid hormone receptor beta2 amino terminus and coactivators

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900043-7

7 January 2021

Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS1043-2760%2802%2900043-7

7 January 2021

10.1016/S1043-2760(02)00043-7

Identifiers

DOI

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1 December 2017

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