(Q44330538)

English

Impact of Mrp2 on the biliary excretion and intestinal absorption of furosemide, probenecid, and methotrexate using Eisai hyperbilirubinemic rats.

scientific article published in January 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Impact of Mrp2 on the biliary excretion and intestinal absorption of furosemide, probenecid, and methotrexate using Eisai hyperbilirubinemic rats (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Dennis O. Scott

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

author name string

Cuiping Chen

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Elizabeth Hanson

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Judy Franco

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Edwin Berryman

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Mario Volberg

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Xingrong Liu

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

publication date

1 January 2003

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

20

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

31-37

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Pharmacokinetic, biliary excretion, and metabolic studies of 14C-furosemide in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic secretion of conjugated drugs and endogenous substances

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of an in vivo preclinical screen model to estimate absorption and bioavailability of xenobiotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both cMOAT/MRP2 and another unknown transporter(s) are responsible for the biliary excretion of glucuronide conjugate of the nonpeptide angiotensin II antagonist, telmisaltan

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiplicity of biliary excretion mechanisms for irinotecan, CPT-11, and its metabolites in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of transport proteins in drug absorption, distribution and excretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-linear elimination and protein binding of probenecid

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and pharmacodynamic changes of furosemide after intravenous and oral administration to rats with alloxan-induced diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different biliary excretion systems for glucuronide and sulfate of a model compound; study using Eisai hyperbilirubinemic rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of biliary excretion of methotrexate by probenecid in rats: quantitative prediction of interaction from in vitro data

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR(-) rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excretion of probenecid and its metabolites in bile and urine of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biliary excretion of 17beta-estradiol 17beta-D-glucuronide is predominantly mediated by cMOAT/MRP2

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of canalicular multispecific organic anion transporter defective in EHBR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and localization of multidrug resistant protein mrp2 in rat small intestine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of probenecid on fluorescein transport in the central nervous system using in vitro and in vivo models

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biliary excretion of pravastatin in rats: contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species differences in oral bioavailability of methotrexate between rats and monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multidrug resistance protein family.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of an organic anion transporter (canalicular multispecific organic anion transporter/multidrug resistance-associated protein 2) in gastrointestinal secretion of glutathione conjugates in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temocaprilat, a novel angiotensin-converting enzyme inhibitor, is excreted in bile via an ATP-dependent active transporter (cMOAT) that is deficient in Eisai hyperbilirubinemic mutant rats (EHBR).

1 reference

https://pubmed.ncbi.nlm.nih.gov/12608533

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1022238506509

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12608533%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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