(Q44339339)

2 December 2017

title

First clinical experience with TRV027: pharmacokinetics and pharmacodynamics in healthy volunteers (English)

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2 December 2017

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David G Soergel

1

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2 December 2017

Ruth Ann Subach

2

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2 December 2017

Conrad L Cowan

3

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2 December 2017

Jonathan D Violin

4

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2 December 2017

Michael W Lark

5

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2 December 2017

language of work or name

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29 June 2013

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The Journal of Clinical Pharmacology

2 December 2017

published in

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2 December 2017

volume

53

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2 December 2017

issue

9

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2 December 2017

page(s)

892-899

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Neurohormonal activation rapidly decreases after intravenous therapy with diuretics and vasodilators for class IV heart failure

2 December 2017

cites work

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Biomarkers in acutely decompensated heart failure with preserved or reduced ejection fraction

21 January 2018

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21 January 2018

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Mitochondria, myocardial remodeling, and cardiovascular disease.

21 January 2018

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Clinical policy: Critical issues in the evaluation and management of adult patients presenting to the emergency department with acute heart failure syndromes

21 January 2018

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Losartan in heart failure. Hemodynamic effects and tolerability. Losartan Hemodynamic Study Group

21 January 2018

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Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes

21 January 2018

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{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation

21 January 2018

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Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference

21 January 2018

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Biased ligands for better cardiovascular drugs: dissecting G-protein-coupled receptor pharmacology.

21 January 2018

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Pharmacologic perspectives of functional selectivity by the angiotensin II type 1 receptor

21 January 2018

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Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.

21 January 2018

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β-Arrestin-biased AT1R stimulation promotes cell survival during acute cardiac injury

21 January 2018

1 reference

Cardiorenal actions of TRV120027, a novel ß-arrestin-biased ligand at the angiotensin II type I receptor, in healthy and heart failure canines: a novel therapeutic strategy for acute heart failure

21 January 2018

1 reference

Untreated heart failure: clinical and neuroendocrine effects of introducing diuretics

21 January 2018

1 reference

Haemodynamic and hormonal responses to oral enalapril in salt depleted normotensive man.

21 January 2018

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Relationship between heart failure treatment and development of worsening renal function among hospitalized patients

21 January 2018

1 reference

Loop diuretics in acute decompensated heart failure: necessary? Evil? A necessary evil?

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCPH.111

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2 December 2017

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