(Q44341121)

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A common human micro-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 December 2017

A common human micro-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

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8

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Europe PubMed Central

PubMed publication ID

2 December 2017

author name string

Bruno Georg Oertel

1

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Europe PubMed Central

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2 December 2017

Mattias Kettner

2

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Europe PubMed Central

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2 December 2017

Klaus Scholich

3

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Europe PubMed Central

PubMed publication ID

2 December 2017

Christoph Renné

4

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Europe PubMed Central

PubMed publication ID

2 December 2017

Bianca Roskam

5

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Europe PubMed Central

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2 December 2017

Gerd Geisslinger

6

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Europe PubMed Central

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2 December 2017

Peter Harald Schmidt

7

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Europe PubMed Central

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2 December 2017

language of work or name

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publication date

30 December 2008

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Europe PubMed Central

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2 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

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2 December 2017

284

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PubMed publication ID

2 December 2017

10

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Europe PubMed Central

PubMed publication ID

2 December 2017

6530-6535

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Europe PubMed Central

PubMed publication ID

2 December 2017

The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Pharmacokinetic-pharmacodynamic modeling of morphine-6-glucuronide-induced analgesia in healthy volunteers: absence of sex differences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Polymorphism of mu-opioid receptor gene (OPRM1:c.118A>G) does not protect against opioid-induced respiratory depression despite reduced analgesic response.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Modulation of Ca2+ channels by heterologously expressed wild-type and mutant human micro-opioid receptors (hMORs) containing the A118G single-nucleotide polymorphism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Human brain mechanisms of pain perception and regulation in health and disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Differential opioid action on sensory and affective cerebral pain processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Psychological and neural mechanisms of the affective dimension of pain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Painful stimuli evoke different stimulus-response functions in the amygdala, prefrontal, insula and somatosensory cortex: a single-trial fMRI study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Comprehensive mu-opioid-receptor genotyping by pyrosequencing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Differences in G-protein activation by mu- and delta-opioid, and cannabinoid, receptors in rat striatum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Relationship of mu opioid receptor binding to activation of G-proteins in specific rat brain regions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Studies of micro-, kappa-, and delta-opioid receptor density and G protein activation in the cortex and thalamus of monkeys.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Characterization of the binding of [3H][Dmt1]H-Dmt-D-Arg-Phe-Lys-NH2, a highly potent opioid peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

COMT Val108/158Met genotype affects the mu-opioid receptor system in the human brain: evidence from ligand-binding, G-protein activation and preproenkephalin mRNA expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

High opiate receptor binding potential in the human lateral pain system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Autoradiographic distribution of multiple classes of opioid receptor binding sites in human forebrain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Autoradiography of receptor-activated G-proteins in post mortem human brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Identification and characterization of two new human mu opioid receptor splice variants, hMOR-1O and hMOR-1X.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Different beta-subunits determine G-protein interaction with transmembrane receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807030200

21 January 2018

Identifiers

10.1074/JBC.M807030200

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 December 2017

ResearchGate publication ID

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