(Q44351630)

2 December 2017

Relevance of frequent mu-opioid receptor polymorphisms for opioid activity in healthy volunteers (English)

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2 December 2017

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1

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2 December 2017

Geisslinger G

2

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2 December 2017

1 May 2006

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The Pharmacogenomics Journal

2 December 2017

1 reference

2 December 2017

6

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2 December 2017

3

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2 December 2017

200-210

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https://scigraph.springernature.com/pub.10.1038/sj.tpj.6500362

2 December 2017

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cites work

Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment

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Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene

21 January 2018

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Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers

21 January 2018

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The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine

21 January 2018

1 reference

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Pharmacokinetic-pharmacodynamic modeling of morphine-6-glucuronide-induced analgesia in healthy volunteers: absence of sex differences

21 January 2018

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Polymorphism of mu-opioid receptor gene (OPRM1:c.118A>G) does not protect against opioid-induced respiratory depression despite reduced analgesic response.

21 January 2018

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The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease

21 January 2018

1 reference

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Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity?

21 January 2018

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Sequence Variability and Candidate Gene Analysis in Two Cancer Patients with Complex Clinical Outcomes During Morphine Therapy

21 January 2018

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Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence

21 January 2018

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Respiratory and miotic effects of morphine in healthy volunteers when P-glycoprotein is blocked by quinidine

21 January 2018

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Probenecid interacts with the pharmacokinetics of morphine-6-glucuronide in humans

21 January 2018

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Are mu-opioid receptor polymorphisms important for clinical opioid therapy?

21 January 2018

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Opioid receptor and peptide gene polymorphisms: potential implications for addictions

21 January 2018

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Comprehensive mu-opioid-receptor genotyping by pyrosequencing

21 January 2018

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Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms

21 January 2018

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Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19

21 January 2018

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Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine

21 January 2018

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A pharmacodynamic model for pancuronium

21 January 2018

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Understanding the dose-effect relationship: clinical application of pharmacokinetic-pharmacodynamic models

21 January 2018

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Limited phase I study of morphine-3-glucuronide

21 January 2018

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Randomized placebo-controlled trial of the activity of the morphine glucuronides

21 January 2018

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The mu-opioid receptor gene polymorphism (A118G) alters HPA axis activation induced by opioid receptor blockade

21 January 2018

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Association between the cortisol response to opioid blockade and the Asn40Asp polymorphism at the mu-opioid receptor locus (OPRM1).

21 January 2018

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Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction

21 January 2018

1 reference

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Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor

21 January 2018

1 reference

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A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling

21 January 2018

1 reference

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Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G.

21 January 2018

1 reference

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Detection of single nucleotide polymorphisms of the human mu opioid receptor gene by hybridization or single nucleotide extension on custom oligonucleotide gelpad microchips: potential in studies of addiction

21 January 2018

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Human mu opioid receptor gene polymorphisms and vulnerability to substance abuse.

21 January 2018

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Mu opioid receptor gene as a candidate for the study of obsessive compulsive disorder with and without tics

21 January 2018

1 reference

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Genetics of two mu opioid receptor gene (OPRM1) exon I polymorphisms: population studies, and allele frequencies in alcohol- and drug-dependent subjects

21 January 2018

1 reference

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Population pharmacokinetics II: estimation methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500362

Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500362

Mu opioid receptor gene variants: lack of association with alcohol dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500362

Simultaneous modeling of pharmacokinetics and pharmacodynamics with nonparametric kinetic and dynamic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500362

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.TPJ.6500362

1 reference

release_vu5tafvkc5hnzoislaml6mwh7u

2 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vu5tafvkc5hnzoislaml6mwh7u

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

16415919

1 reference

PubMed ID

16415919