(Q44363642)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639557%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Exploring new non-sugar sulfated molecules as activators of antithrombin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639557%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639557%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

Gunnar T Gunnarsson

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639557%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 February 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639557%20AND%20SRC:MED&resulttype=core&format=json

Bioorganic & Medicinal Chemistry Letters

1 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639557%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639557%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639557%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

679-683

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639557%20AND%20SRC:MED&resulttype=core&format=json

An update on heparins at the beginning of the new millennium

1 November 2019

cites work

1 reference

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7 January 2021

Low molecular weight heparins: are they superior to unfractionated heparins to prevent and to treat deep vein thrombosis?

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7 January 2021

The role of low-molecular-weight heparins in arterial diseases: optimizing antithrombotic therapy

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7 January 2021

Low-molecular-weight heparin: prophylaxis and treatment of venous thromboembolism

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7 January 2021

State of the art--a journey through the world of antithrombotic therapy

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7 January 2021

The role of low-molecular-weight heparin in cardiovascular diseases

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7 January 2021

Fondaparinux compared with enoxaparin for the prevention of venous thromboembolism after hip-fracture surgery.

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7 January 2021

Sugars slide into heparin activity

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7 January 2021

Mode of interaction between platelet factor 4 and heparin

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7 January 2021

Synthesis of thrombin-inhibiting heparin mimetics without side effects

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7 January 2021

Structural studies on a biologically active hexasaccharide obtained from heparin

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7 January 2021

Structure-activity relationship in heparin: a synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity

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7 January 2021

Mechanism of heparin activation of antithrombin. Role of individual residues of the pentasaccharide activating sequence in the recognition of native and activated states of antithrombin.

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7 January 2021

Mechanism of heparin activation of antithrombin: evidence for an induced-fit model of allosteric activation involving two interaction subsites

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7 January 2021

Mechanism of heparin activation of antithrombin. Evidence for reactive center loop preinsertion with expulsion upon heparin binding

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7 January 2021

The anticoagulant activation of antithrombin by heparin

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7 January 2021

Conformational changes in serpins: II. The mechanism of activation of antithrombin by heparin.

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7 January 2021

Designing small, nonsugar activators of antithrombin using hydropathic interaction analyses.

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7 January 2021

Synthesis of heparin fragments. A chemical synthesis of the pentasaccharide O-(2-deoxy-2-sulfamido-6-O-sulfo-alpha-D-glucopyranosyl)-(1-4 )-O-(beta-D-glucopyranosyluronic acid)-(1-4)-O-(2-deoxy-2-sulfamido-3,6-di-O-sulfo-alpha-D-glu copyranosyl)-(1-

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7 January 2021

Anticoagulant effect and action mechanism of sulphated flavonoids from Flaveria bidentis

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7 January 2021

The region of antithrombin interacting with full-length heparin chains outside the high-affinity pentasaccharide sequence extends to Lys136 but not to Lys139.

1 reference

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7 January 2021

Critical role of the linker region between helix D and strand 2A in heparin activation of antithrombin

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7 January 2021

Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin.

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7 January 2021