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Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways.
scientific article published in April 2003
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Europe PubMed Central
PubMed publication ID
12660005
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1 November 2019
title
Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways
(English)
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Europe PubMed Central
PubMed publication ID
12660005
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1 November 2019
author
José A Sánchez-Alcázar
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1
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Europe PubMed Central
PubMed publication ID
12660005
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1 November 2019
Alan Knox
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4
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Europe PubMed Central
PubMed publication ID
12660005
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1 November 2019
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Dawn A Bradbury
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2
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Europe PubMed Central
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12660005
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1 November 2019
Linhua Pang
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3
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PubMed publication ID
12660005
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1 November 2019
publication date
1 April 2003
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Europe PubMed Central
PubMed publication ID
12660005
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1 November 2019
published in
Lung Cancer
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Europe PubMed Central
PubMed publication ID
12660005
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12660005%20AND%20SRC:MED&resulttype=core&format=json
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1 November 2019
volume
40
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Europe PubMed Central
PubMed publication ID
12660005
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12660005%20AND%20SRC:MED&resulttype=core&format=json
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1 November 2019
issue
1
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Europe PubMed Central
PubMed publication ID
12660005
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1 November 2019
page(s)
33-44
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Europe PubMed Central
PubMed publication ID
12660005
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12660005%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
cites work
Why there are two cyclooxygenase isozymes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The COX-1/COX-2 balance in asthma
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Crossref
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7 January 2021
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Aspirin and other anti-inflammatory drugs
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Crossref
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https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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Non-steroidal anti-inflammatory drugs: back to the future
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Crossref
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7 January 2021
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inferred from DOI database lookup
Colorectal cancer and nonsteroidal anti-inflammatory drugs.
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma
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Crossref
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7 January 2021
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Cyclooxygenase-2 expression in human pancreatic adenocarcinomas
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7 January 2021
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Prostaglandins and human lung carcinomas
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7 January 2021
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Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
1 reference
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reference URL
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7 January 2021
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Cyclooxygenase regulates angiogenesis induced by colon cancer cells
1 reference
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Crossref
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7 January 2021
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Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in vitro invasion of tumor cells
1 reference
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Crossref
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Chemoprevention of spontaneous intestinal adenomas in the adenomatous polyposis coli Min mouse model with aspirin.
1 reference
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7 January 2021
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Sulindac suppresses tumorigenesis in the Min mouse.
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7 January 2021
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Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
1 reference
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Reduction of carcinogenicity of N-nitrosomethylurea by indomethacin and failure of resuming effect of prostaglandin E2 (PGE2) against indomethacin
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Tumor Necrosis Factor-α Increases the Steady-state Reduction of Cytochromebof the Mitochondrial Respiratory Chain in Metabolically Inhibited L929 Cells
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Tumor necrosis factor-alpha increases ATP content in metabolically inhibited L929 cells preceding cell death.
1 reference
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Production of PGE2 by bovine cultured airway smooth muscle cells and its inhibition by cyclo-oxygenase inhibitors
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Human airway smooth muscle cells secrete vascular endothelial growth factor: up-regulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism.
1 reference
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7 January 2021
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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.
1 reference
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Crossref
reference URL
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7 January 2021
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Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
1 reference
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7 January 2021
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Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release
1 reference
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Crossref
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7 January 2021
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1 reference
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Crossref
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7 January 2021
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Molecular characterization of mitochondrial apoptosis-inducing factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
1 reference
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7 January 2021
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Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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inferred from DOI database lookup
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Bax directly induces release of cytochrome c from isolated mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
1 reference
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The concerted regulation of cPLA2, COX2, and lipocortin 1 expression by IL-1beta in A549 cells
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https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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Peroxisome proliferator-activated receptor-gamma is a target of nonsteroidal anti-inflammatory drugs mediating cyclooxygenase-independent inhibition of lung cancer cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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inferred from DOI database lookup
Selectivity of cyclo-oxygenase inhibitors in human pulmonary epithelial and smooth muscle cells.
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system.
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
CED-4--the third horseman of apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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inferred from DOI database lookup
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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inferred from DOI database lookup
Mammalian caspases: structure, activation, substrates, and functions during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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inferred from DOI database lookup
The mitochondrial electron transport and oxidative phosphorylation system
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Bcl-2 protein family
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Indomethacin-induced apoptosis in esophageal adenocarcinoma cells involves upregulation of Bax and translocation of mitochondrial cytochrome C independent of COX-2 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
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inferred from DOI database lookup
Radiation-induced apoptosis in human myeloma cell line increases BCL-2/BAX dimer formation and does not result in BAX/BAX homodimerization
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
The binding properties and biological activities of Bcl-2 and Bax in cells exposed to apoptotic stimuli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of indomethacin on mitochondrial oxygen uptake in intestine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of indomethacin on mitochondrial ATP synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition and uncoupling of oxidative phosphorylation by nonsteroidal anti-inflammatory drugs: study in mitochondria, submitochondrial particles, cells, and whole heart
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria and cell death. Mechanistic aspects and methodological issues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria and programmed cell death: back to the future.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0169-5002%2802%2900530-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0169-5002(02)00530-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12660005
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12660005%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PubMed publication ID
12660005
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12660005
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12660005%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
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