(Q44380124)

2 December 2017

Protease inhibition causes some manifestations of aging and Alzheimer's disease in rodent and primate brain (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1337691

15 September 2022

0 references

0 references

G. O. Ivy

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1337691

15 September 2022

language of work or name

English

0 references

publication date

1 December 1992

1 reference

2 December 2017

31 December 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1337691

Annals of the New York Academy of Sciences

15 September 2022

published in

1 reference

2 December 2017

674

1 reference

2 December 2017

89-102

1 reference

Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease

2 December 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

The carboxyl third of tau is tightly bound to paired helical filaments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Structural stability of paired helical filaments requires microtubule-binding domains of Tau: A model for self-association

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Ubiquitin-protein conjugates in Alzheimer's lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Ubiquitin is a component of paired helical filaments in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Ubiquitin is a component of neurofibrillary tangles in a variety of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodie

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Diffuse Lewy body disease: light and electron microscopic immunocytochemistry of senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Evidence for the lack of lysosomal involvement in the age-related slowing of protein breakdown in Turbatrix aceti

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Inhibitors of lysosomal enzymes: accumulation of lipofuscin-like dense bodies in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Anomalous accumulation of tau and ubiquitin immunoreactivities in rat brain caused by protease inhibition and by normal aging: a clue to PHF pathogenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Leupeptin causes an accumulation of lipofuscin-like substances in liver cells of young rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

The protease inhibitor leupeptin induces several signs of aging in brain, retina and internal organs of young rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Protease inhibitors as a model for NCL disease, with special emphasis on the infantile and adult forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Electron microscopic studies on the lipo-pigments in the cerebral cortex nerve cells of senile and vitamin E deficient rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Inhibition of proteolytic activity of calcium activated neutral protease by leupeptin and antipain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Effects of chloroquine on lysosomal enzymes, NADPH-induced lipid peroxidation, and antioxidant enzymes of rat retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Metabolism of [3H]leupeptin by rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Degradation of the acetylcholine receptor in cultured muscle cells: selective inhibitors and the fate of undegraded receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Ubiquitinated protein conjugates are specifically enriched in the lysosomal system of fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Calcium-activated neutral protease (CANP) in brain and other tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Brain ubiquitin is markedly elevated in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Massive somatodendritic sprouting of cortical neurons in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Phosphorylation of microtubule-associated proteins by a Ca2+/calmodulin-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

The effects of aging and chronic dietary restriction on whole body growth and protein turnover in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Food Restriction Enhances the Proteolytic Capacity of the Aging Rat Liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Decreased protein and puromycinyl-peptide degradation in livers of senescent mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Effect of age on the expression of antioxidant enzymes in male Fischer F344 rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Red cell superoxide dismutase, glutathione peroxidase and catalase in Down syndrome patients with and without manifestations of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Abnormal distribution of cathepsins in the brain of patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Calpain and calpastatin in normal and Alzheimer-degenerated human brain tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Presence of calpain II immunoreactivity in senile plaques in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Effect of leupeptin on the lateral mobility of proteins in the plasma membrane of hepatocytes of C57BL/6 mice: FRAP studies on liver smears.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

Ubiquitin immunoelectron microscopy of dystrophic neurites in cerebellar senile plaques of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1992.TB27479.X

10.1111/J.1749-6632.1992.TB27479.X

21 January 2018

Identifiers

DOI

1 reference

2 December 2017

1 reference