(Q44385966)

2 December 2017

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title

A brief history of novel drug discovery technologies (English)

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2 December 2017

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Leland J Gershell

1

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2 December 2017

Joshua H Atkins

series ordinal

2

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2 December 2017

publication date

1 April 2003

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Nature Reviews Drug Discovery

2 December 2017

published in

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2 December 2017

volume

2

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2 December 2017

issue

4

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2 December 2017

page(s)

321-327

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Synthesis of mixed oligodeoxyribonucleotides following the solid phase method.

2 December 2017

cites work

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Continuous cultures of fused cells secreting antibody of predefined specificity

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The impact of genomics on drug discovery

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Knockouts model the 100 best-selling drugs--will they model the next 100?

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Apoptosis and chemoresistance in transgenic cancer models

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Chimeric snRNA molecules carrying antisense sequences against the splice junctions of exon 51 of the dystrophin pre-mRNA induce exon skipping and restoration of a dystrophin synthesis in Delta 48-50 DMD cells

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Design and therapeutic application of matrix metalloproteinase inhibitors

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Drug-like properties and the causes of poor solubility and poor permeability

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The properties of known drugs. 1. Molecular frameworks

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A gene expression database for the molecular pharmacology of cancer

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Protein microarrays: prospects and problems

31 March 2020

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Better therapeutics through microarrays

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ADMET--turning chemicals into drugs

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31 March 2020

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31 March 2020

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High-throughput approaches for evaluating absorption, distribution, metabolism and excretion properties of lead compounds

31 March 2020

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

31 March 2020

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The emerging importance of predictive ADME simulation in drug discovery

31 March 2020

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HIV integrase, a brief overview from chemistry to therapeutics

31 March 2020

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Fully automated two-dimensional capillary electrophoresis for high sensitivity protein analysis

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Milestones in directed enzyme evolution.

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Nucleic acid and polypeptide aptamers: a powerful approach to ligand discovery.

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31 March 2020

Identifiers

DOI

10.1038/NRD1064

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2 December 2017

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