(Q44392730)

2 December 2017

title

Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase (English)

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2 December 2017

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1

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2 December 2017

Maria José Casarejos

2

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2 December 2017

Sonsoles de Bernardo

series ordinal

3

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2 December 2017

Eulalia Rodríguez-Martín

series ordinal

4

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2 December 2017

Maria Angeles Mena

series ordinal

5

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2 December 2017

language of work or name

English

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publication date

4 April 2003

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Journal of Biological Chemistry

2 December 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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2 December 2017

volume

278

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2 December 2017

issue

24

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2 December 2017

page(s)

21542-21549

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Oxidative stress and the pathogenesis of Parkinson's disease

2 December 2017

cites work

1 reference

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Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

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Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

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An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease

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Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study

21 January 2018

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Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

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Detection of nitrosyl complexes in human substantia nigra, in relation to Parkinson's disease.

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Protein nitration in Parkinson's disease.

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Tetrahydrobiopterin scavenges superoxide in dopaminergic neurons

21 January 2018

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Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease

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Neurotrophic and neurotoxic effects of nitric oxide on fetal midbrain cultures

21 January 2018

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Arachidonic acid cascade and signal transduction

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Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signalling

21 January 2018

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Involvement of glutamate receptors, lipases, and phospholipases in long-term potentiation and neurodegeneration

21 January 2018

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A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion.

21 January 2018

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Nitric oxide activates the glucose-dependent mobilization of arachidonic acid in a macrophage-like cell line (RAW 264.7) that is largely mediated by calcium-independent phospholipase A2.

21 January 2018

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Peroxynitrite-mediated release of arachidonic acid from PC12 cells

21 January 2018

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Nitric oxide responsible for NMDA receptor-evoked inhibition of arachidonic acid incorporation into lipids of brain membrane.

21 January 2018

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Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture

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Neuronal-enriched cultures from embryonic rat ventral mesencephalon for pharmacological studies of dopamine neurons.

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Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system

21 January 2018

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pH-dependent fluorescence of DNA and RNA in cytologic staining with “33258 Hoechst”

21 January 2018

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A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity

21 January 2018

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Glial cells mediate toxicity in glutathione-depleted mesencephalic cultures

21 January 2018

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Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi

21 January 2018

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Ascorbate regulation and its neuroprotective role in the brain

21 January 2018

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Requirement for cGMP in nerve cell death caused by glutathione depletion

21 January 2018

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The neuronal toxicity of sulfite plus peroxynitrite is enhanced by glutathione depletion: implications for Parkinson's disease

21 January 2018

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G-protein beta gamma-subunits activate the cardiac muscarinic K+-channel via phospholipase A2

21 January 2018

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Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione.

21 January 2018

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Thiolic antioxidants protect from nitric oxide-induced toxicity in fetal midbrain cultures

21 January 2018

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Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

21 January 2018

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Protective effect of quinacrine on striatal dopamine levels in 6-OHDA and MPTP models of Parkinsonism in rodents

21 January 2018

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Properties and regulation of cytosolic phospholipase A2.

21 January 2018

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Final common pathways in neurodegenerative diseases: regulatory role of the glutathione cycle

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M213174200

Arachidonate 12-lipoxygenases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M213174200

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

21 January 2018

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Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

21 January 2018

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Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

21 January 2018

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Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease

21 January 2018

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Increased cerebrospinal fluid concentration of nitrite in Parkinson's disease

21 January 2018

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Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones.

21 January 2018

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Glutathione depletion in rat brain does not cause nigrostriatal pathway degeneration

21 January 2018

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Preferential resistance of dopaminergic neurons to the toxicity of glutathione depletion is independent of cellular glutathione peroxidase and is mediated by tetrahydrobiopterin

21 January 2018

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Reduction of brain glutathione by L-buthionine sulfoximine potentiates the dopamine-depleting action of 6-hydroxydopamine in rat striatum

21 January 2018

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Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism

21 January 2018

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Levodopa toxicity in foetal rat midbrain neurones in culture: modulation by ascorbic acid.

21 January 2018

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Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

21 January 2018

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Inhibition of soybean lipoxygenase by SKF 525-A and metyrapone

21 January 2018

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The sensitivity of bovine corneal epithelial lyso-PAF acetyltransferase to cyclooxygenase and lipoxygenase inhibitors is independent of arachidonate metabolites

21 January 2018

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Activity and protein distribution of 12-lipoxygenase in HEL cells: induction of membrane-association by phorbol ester TPA, modulation of activity by glutathione and 13-HPODE, and Ca(2+)-dependent translocation to membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213174200

Nitric oxide synthase and neuronal vulnerability in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213174200

21 January 2018

Identifiers

DOI

10.1074/JBC.M213174200

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2 December 2017

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