(Q44395811)

2 December 2017

The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities (English)

1 reference

2 December 2017

Erica Friedrich-Heineken

1

1 reference

2 December 2017

Ghislaine Henneke

2

1 reference

2 December 2017

Elena Ferrari

3

1 reference

2 December 2017

Ulrich Hübscher

4

1 reference

2 December 2017

language of work or name

English

0 references

publication date

1 April 2003

1 reference

Journal of Molecular Biology

2 December 2017

1 reference

2 December 2017

328

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2 December 2017

73-84

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2 December 2017

1

1 reference

The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

2 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Flap endonuclease homologs in archaebacteria exist as independent proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Enzymes and reactions at the eukaryotic DNA replication fork

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing events

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Conditional lethality of null mutations in RTH1 that encodes the yeast counterpart of a mammalian 5'- to 3'-exonuclease required for lagging strand DNA synthesis in reconstituted systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Vertebrate cells lacking FEN-1 endonuclease are viable but hypersensitive to methylating agents and H2O2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

The crystal structure of flap endonuclease-1 from Methanococcus jannaschii

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Calf 5' to 3' exo/endonuclease must slide from a 5' end of the substrate to perform structure-specific cleavage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

The characterization of a mammalian DNA structure-specific endonuclease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Arginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

A comparison of eubacterial and archaeal structure-specific 5'-exonucleases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

DNA structural elements required for FEN-1 binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Coordination between the polymerase and 5'-nuclease components of DNA polymerase I of Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

In eukaryotic flap endonuclease 1, the C terminus is essential for substrate binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Processing of branched DNA intermediates by a complex of human FEN-1 and PCNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

Essential amino acids for substrate binding and catalysis of human flap endonuclease 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering 1 1Edited by M. F. Moody

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900270-5

10.1016/S0022-2836(03)00270-5

7 January 2021

Identifiers

DOI

1 reference

2 December 2017

1 reference