(Q44398258)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Complex haplotypes of IRS2 gene are associated with severe obesity and reveal heterogeneity in the effect of Gly1057Asp mutation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

Corinne Lautier

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Samira Ait El Mkadem

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Eric Renard

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Jean Frédéric Brun

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Jacques Bringer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Florin Grigorescu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

publication date

10 April 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

34-43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12687350%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00439-003-0935-3

2 November 2019

exact match

0 references

cites work

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Variations in insulin secretion in carriers of gene variants in IRS-1 and -2.

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The prevalent Gly1057Asp polymorphism in the insulin receptor substrate-2 gene is not associated with impaired insulin secretion

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Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity.

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Increased insulin sensitivity and basal insulin effectiveness in postprandial reactive hypoglycaemia

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12 December 2020

Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome

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12 December 2020

Genetic epidemiology of single-nucleotide polymorphisms.

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12 December 2020

The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance.

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12 December 2020

The predictive power of haplotypes in clinical response

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A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies

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IRS-2 pathways integrate female reproduction and energy homeostasis

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Disruption of IRS-2 causes type 2 diabetes in mice

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Exclusion of insulin receptor substrate 2 (IRS-2) as a major locus for early-onset autosomal dominant type 2 diabetes

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Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus

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Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians.

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Statistical estimation and pedigree analysis of CCR2-CCR5 haplotypes

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The future of genetic studies of complex human diseases

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Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene

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12 December 2020

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Genetics of insulin resistance

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12 December 2020

Equivalence of single- and multilocus markers: power to detect linkage with composite markers derived from biallelic loci

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12 December 2020

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12 December 2020

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

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12 December 2020

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12 December 2020

In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin

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12 December 2020

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12 December 2020

Human insulin receptor substrate-2: gene organization and promoter characterization

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12 December 2020

Role of IRS-2 in insulin and cytokine signalling

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12 December 2020

Homeostasis model assessment and related simplified evaluations of insulin sensitivity from fasting insulin and glucose.

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12 December 2020

A New Statistical Method for Haplotype Reconstruction from Population Data

1 reference

12 December 2020

Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes.

1 reference

12 December 2020

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

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