(Q44407124)

2 December 2017

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Increased anxiety 3 months after brief exposure to MDMA ("Ecstasy") in rats: association with altered 5-HT transporter and receptor density (English)

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2 December 2017

Iain S McGregor

1

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2 December 2017

Kelly J Clemens

2

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2 December 2017

Geoffrey Van der Plasse

3

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2 December 2017

Kong M Li

4

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2 December 2017

Glenn E Hunt

5

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2 December 2017

Feng Chen

6

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2 December 2017

Andrew J Lawrence

7

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2 December 2017

language of work or name

English

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publication date

16 April 2003

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2 December 2017

Neuropsychopharmacology

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2 December 2017

28

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2 December 2017

1472-1484

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2 December 2017

8

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1300185

2 December 2017

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cites work

MDMA ('Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Pharmacological studies of the acute effects of (+)-3,4-methylenedioxymethamphetamine on locomotor activity: role of 5-HT(1B/1D) and 5-HT(2) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): assessment using quantitative autoradiography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

MDMA- and p-chlorophenylalanine-induced reduction in 5-HT concentrations: effects on serotonin transporter densities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Long-term impairment of anterograde axonal transport along fiber projections originating in the rostral raphe nuclei after treatment with fenfluramine or methylenedioxymethamphetamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

An autoradiographic study of serotonergic receptors in a murine genetic model of anxiety-related behaviors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Studies on the neuroprotective effect of the enantiomers of AR-A008055, a compound structurally related to clomethiazole, on MDMA ("ecstasy")-induced neurodegeneration in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

The hyperthermic and neurotoxic effects of 'Ecstasy' (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Differential effects of serotonin (5-HT) lesions and synthesis blockade on neuropeptide-Y immunoreactivity and 5-HT1A, 5-HT1B/1D and 5-HT2A/2C receptor binding sites in the rat cerebral cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Selective increases in serotonin 5-HT1B/1D and 5-HT2A/2C binding sites in adult rat basal ganglia following lesions of serotonergic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

3,4-Methylenedioxymethamphetamine produces glycogenolysis and increases the extracellular concentration of glucose in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

"When a rat smells a cat": the distribution of Fos immunoreactivity in rat brain following exposure to a predatory odor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Role of the dorsomedial hypothalamus in mediating the response to benzodiazepines on trial 2 in the elevated plus-maze test of anxiety.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Stereoselective pharmacokinetics of 3,4-methylenedioxymethamphetamine in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Long-term changes in social interaction and reward following repeated MDMA administration to adolescent rats without accompanying serotonergic neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

The effect of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Mood state and brain electric activity in ecstasy users.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

MDMA stimulus generalization to the 5-HT(1A) serotonin agonist 8-hydroxy-2- (di-n-propylamino)tetralin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Effect of the repeated administration of (+/-)-3,4-methylenedioxymethamphetamine on the behavioral response of rats to the 5-HT1A receptor agonist (+/-)-8-hydroxy-(di-n-propylamino)tetralin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Environmental enrichment decreases intravenous amphetamine self-administration in rats: dose-response functions for fixed- and progressive-ratio schedules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: more than 30 years of research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

A comparative study of the effects of selective and non-selective 5-HT2 receptor subtype antagonists in rat and mouse models of anxiety.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Increased anxiety in rats after 3,4-methylenedioxymethamphetamine: association with serotonin depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Prior exposure to methylenedioxyamphetamine (MDA) induces serotonergic loss and changes in spontaneous exploratory and amphetamine-induced behaviors in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Effects of chronic antidepressant treatments on 5-HT and NA transporters in rat brain: an autoradiographic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Effects of the selective 5-HT2A receptor antagonist MDL 100,907 on MDMA-induced locomotor stimulation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Binding of 5-HT1A receptor and 5-HT transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Altered neuroendocrine and behavioral responses to m-chlorophenylpiperazine in 3,4-methylenedioxymethamphetamine (MDMA) users.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Positron emission tomographic evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurons in human beings.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long-term defect in thermoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Ecstasy (MDMA): a review of its possible persistent psychological effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine ("ecstasy").

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA ('ecstasy').

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Serotonin receptor 1A knockout: an animal model of anxiety-related disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Fluvoxamine treatment of mixed anxiety and depression: evidence for serotonergically mediated anxiolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Use of amphetamine by recreational users of ecstasy (MDMA) is associated with reduced striatal dopamine transporter densities: a [123I]beta-CIT SPECT study--preliminary report

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Memory disturbances in "Ecstasy" users are correlated with an altered brain serotonin neurotransmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

The acute and chronic effects of MDMA ("ecstasy") on cortical 5-HT2A receptors in rat and human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Hallucinogenic amphetamine selectively destroys brain serotonin nerve terminals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Retracted article on dopaminergic neurotoxicity of MDMA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Enhanced aggressive behavior in mice lacking 5-HT1B receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Locomotor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Repeated administration of MDMA causes transient down-regulation of serotonin 5-HT2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

MDMA ('ecstasy') consumption in the context of polydrug abuse: a report on 150 patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Cholinergic modulation of the release of 5-hydroxytryptamine from the guinea pig ileum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Dorsomedial hypothalamic GABA regulates anxiety in the social interaction test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Perturbed dentate gyrus function in serotonin 5-HT2C receptor mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Cognitive performance and serotonergic function in users of ecstasy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Working memory deficits in current and previous users of MDMA ('ecstasy').

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

Methylenedioxymethamphetamine induces opposite changes in central pre- and postsynaptic 5-HT1A receptors in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

MDMA (Ecstasy) neurotoxicity: assessing and communicating the risks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

Overexpression of 5-HT1B receptor in dorsal raphe nucleus using Herpes Simplex Virus gene transfer increases anxiety behavior after inescapable stress.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

5-HT1B receptor knock-out mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA ('ecstasy') users

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

(+) 3,4-methylenedioxymethamphetamine ('ecstasy') transiently increases striatal 5-HT1B binding sites without altering 5-HT1B mRNA in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

Ecstasy use in Australia: patterns of use and associated harm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

Quantitative autoradiography of multiple 5-HT1 receptor subtypes in the brain of control or 5,7-dihydroxytryptamine-treated rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300185

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1300185

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Dimensions Publication ID

2 December 2017

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1 reference