(Q44407127)

2 December 2017

Micromolar Brain Levels of Kynurenic Acid are Associated with a Disruption of Auditory Sensory Gating in the Rat (English)

1 reference

https://api.crossref.org/works/10.1038/SJ.NPP.1300188

25 December 2023

1 reference

https://api.crossref.org/works/10.1038/SJ.NPP.1300188

25 December 2023

author name string

Brian Joy

2

1 reference

2 December 2017

Lucy Clerkin

3

1 reference

2 December 2017

Robert Schwarcz

4

1 reference

2 December 2017

Paul D. Shepard

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700696

25 December 2023

language of work or name

English

0 references

publication date

16 April 2003

1 reference

full work available at URL

2 December 2017

https://www.nature.com/articles/1300188.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12700696

http://www.nature.com/articles/1300188.pdf

25 December 2023

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.NPP.1300188

http://www.nature.com/articles/1300188

25 December 2023

1 reference

https://api.crossref.org/works/10.1038/SJ.NPP.1300188

25 December 2023

published in

Neuropsychopharmacology

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2 December 2017

28

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2 December 2017

8

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2 December 2017

1454-1462

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1300188

2 December 2017

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Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors

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Kynurenic acid antagonises responses to NMDA via an action at the strychnine-insensitive glycine receptor

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Response to the first stimulus determines reduced auditory evoked response suppression in schizophrenia: single trials analysis using MEG.

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Structural evaluation of the prefrontal cortex in schizophrenia.

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Sensory gating deficits assessed by the P50 event-related potential in subjects with schizotypal personality disorder

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Multiple site evaluation of P50 suppression among schizophrenia and normal comparison subjects

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Poor P50 suppression among schizophrenia patients and their first-degree biological relatives

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Kynurenine hydroxylase inhibitors reduce ischemic brain damage: studies with (m-nitrobenzoyl)-alanine (mNBA) and 3,4-dimethoxy-[-N-4-(nitrophenyl)thiazol-2yl]-benzenesulfonamide (Ro 61-8048) in models of focal or global brain ischemia.

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Neurophysiological and neuropsychological evidence for attentional dysfunction in schizophrenia.

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Kynurenate and 2-amino-5-phosphonovalerate interact with multiple binding sites of the N-methyl-D-aspartate-sensitive glutamate receptor domain

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Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia

21 January 2018

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P50 abnormalities in schizophrenia: relationship to clinical and neuropsychological indices of attention.

21 January 2018

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Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

21 January 2018

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Blood?Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

21 January 2018

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Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection

21 January 2018

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Interference with cellular energy metabolism reduces kynurenic acid formation in rat brain slices: reversal by lactate and pyruvate.

21 January 2018

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Effects of P50 temporal variability on sensory gating in schizophrenia.

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A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists

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The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential

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Nicotinic receptor function in schizophrenia

21 January 2018

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N-methyl-D-aspartate receptor antagonists are less effective in blocking long-term potentiation at apical than basal dendrites in hippocampal CA1 of awake rats

21 January 2018

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Human and animal studies of schizophrenia-related gating deficits

21 January 2018

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Cholinergic gating of response to auditory stimuli in rat hippocampus

21 January 2018

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On closed testing procedures with special reference to ordered analysis of variance

21 January 2018

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Phencyclidine and auditory sensory gating in the hippocampus of the rat

21 January 2018

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Medial septal neuron activity in relation to an auditory sensory gating paradigm.

21 January 2018

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The effect of peripheral loading with kynurenine and probenecid on extracellular striatal kynurenic acid concentrations.

21 January 2018

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Presence of Kynurenic Acid in the Mammalian Brain

21 January 2018

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Modulation of [3H]MK-801 binding to NMDA receptors in vivo and in vitro.

21 January 2018

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Effects of temporal variability on p50 and the gating ratio in schizophrenia: a frequency domain adaptive filter single-trial analysis

21 January 2018

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Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase.

21 January 2018

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Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires.

21 January 2018

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Kynurenic acid: a potential pathogen in brain disorders.

21 January 2018

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Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities

21 January 2018

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Increased cortical kynurenate content in schizophrenia

21 January 2018

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Concurrent assessment of acoustic startle and auditory P50 evoked potential measures of sensory inhibition.

21 January 2018

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Deficits in sensory gating in schizophrenic patients and their relatives. Evidence obtained with auditory evoked responses.

21 January 2018

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Kynurenines in the CNS: from endogenous obscurity to therapeutic importance

21 January 2018

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On the disposition of intrahippocampally injected kynurenic acid in the rat.

21 January 2018

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Neural correlates of sensory gating in the rat: decreased Fos induction in the lateral septum.

21 January 2018

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Codistribution of a sensory gating deficit and schizophrenia in multi-affected families

21 January 2018

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Restoration of sensory gating of auditory evoked response by nicotine in fimbria-fornix lesioned rats

21 January 2018

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7 January 2021

Replication and extension of P50 findings in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300188

7 January 2021

Allosteric modulation of the glutamate site on the NMDA receptor by four novel glycine site antagonists

1 reference

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7 January 2021

Metabolism of [5‐3H]Kynurenine in the Rat Brain In Vivo: Evidence for the Existence of a Functional Kynurenine Pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300188

7 January 2021

The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

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7 January 2021

Disorders of attention and perception in early schizophrenia

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7 January 2021

Long-term potentiation disrupts auditory gating in the rat hippocampus

1 reference

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7 January 2021

Systemic DL-kynurenine and probenecid pretreatment attenuates quinolinic acid-induced neurotoxicity in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300188

7 January 2021

Quantitative differences in the effects of de novo produced and exogenous kynurenic acid in rat brain slices

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300188

7 January 2021

Kynurenergic manipulations influence excitatory synaptic function and excitotoxic vulnerability in the rat hippocampus in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300188

7 January 2021

Systemic administration of 4-chlorokynurenine prevents quinolinate neurotoxicity in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300188

7 January 2021

Biological Psychiatry

2

17

639

LE Adler

1982

1 reference

https://api.crossref.org/works/10.1038/SJ.NPP.1300188

25 December 2023

Pharmacological Reviews

20

50

597

W Danysz

1998

1 reference

https://api.crossref.org/works/10.1038/SJ.NPP.1300188

25 December 2023

Identifiers

1 reference

2 December 2017

1 reference