(Q44411462)

English

Glatiramer Acetate (Copolymer-1, Copaxone) Promotes Th2 Cell Development and Increased IL-10 Production Through Modulation of Dendritic Cells

scientific article published on May 1, 2003

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scholarly article

1 reference

Europe PubMed Central

2 December 2017

Glatiramer acetate (copolymer-1, copaxone) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells (English)

1 reference

Europe PubMed Central

2 December 2017

Glatiramer Acetate (Copolymer-1, Copaxone) Promotes Th2 Cell Development and Increased IL-10 Production Through Modulation of Dendritic Cells (English)

1 reference

10.4049/JIMMUNOL.170.9.4483

https://api.crossref.org/works/10.4049/JIMMUNOL.170.9.4483

26 December 2023

1 reference

based on heuristic

inferred from title

1 reference

10.4049/JIMMUNOL.170.9.4483

https://api.crossref.org/works/10.4049/JIMMUNOL.170.9.4483

26 December 2023

author name string

Jan Wormmeester

3

1 reference

Europe PubMed Central

2 December 2017

Pedro L. Vieira

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707324

26 December 2023

Heleen C. Heystek

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707324

26 December 2023

Eddy A. Wierenga

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707324

26 December 2023

Martien L. Kapsenberg

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707324

26 December 2023

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publication date

1 May 2003

1 reference

Europe PubMed Central

2 December 2017

number of pages

6

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Journal of Immunology

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Europe PubMed Central

2 December 2017

170

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Europe PubMed Central

2 December 2017

9

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Europe PubMed Central

2 December 2017

4483-4488

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Europe PubMed Central

2 December 2017

Dendritic cells and the control of immunity

1

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10.4049/JIMMUNOL.170.9.4483

https://api.crossref.org/works/10.4049/JIMMUNOL.170.9.4483

26 December 2023

The expanding universe of T-cell subsets: Th1, Th2 and more.

2

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Cytokines induce the development of functionally heterogeneous T helper cell subsets

3

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal

4

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Modulating the immune response with dendritic cells and their growth factors

5

1 reference

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Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells.

8

1 reference

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26 December 2023

High-level IL-12 production by human dendritic cells requires two signals

9

1 reference

10.4049/JIMMUNOL.170.9.4483

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Maturation, activation, and protection of dendritic cells induced by double-stranded RNA

10

1 reference

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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation

11

1 reference

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26 December 2023

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

12

1 reference

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26 December 2023

Histamine polarizes human dendritic cells into Th2 cell-promoting effector dendritic cells

15

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL-10 prime naive CD4+ T cells to secrete IL-4

16

1 reference

10.4049/JIMMUNOL.170.9.4483

https://api.crossref.org/works/10.4049/JIMMUNOL.170.9.4483

26 December 2023

Effect of interleukin-10 on dendritic cell maturation and function

17

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Inhibition of human dendritic cell functions by methylprednisolone.

18

1 reference

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26 December 2023

Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12.

19

1 reference

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Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide

20

1 reference

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26 December 2023

Copolymer 1 inhibits chronic relapsing experimental allergic encephalomyelitis induced by proteolipid protein (PLP) peptides in mice and interferes with PLP-specific T cell responses

21

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

The autoimmune reactivity to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis is potentially pathogenic: effect of copolymer 1 on MOG-induced disease

22

1 reference

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Synthetic amino acid copolymers that bind to HLA-DR proteins and inhibit type II collagen-reactive T cell clones

23

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

A synthetic random basic copolymer with promiscuous binding to class II major histocompatibility complex molecules inhibits T-cell proliferative responses to major and minor histocompatibility antigens in vitro and confers the capacity to prevent mu

24

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Studies on the mechanism and specificity of the effect of the synthetic random copolymer GLAT on graft-versus-host disease

25

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Copolymer 1 inhibits manifestations of graft rejection

26

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group

27

1 reference

10.4049/JIMMUNOL.170.9.4483

https://api.crossref.org/works/10.4049/JIMMUNOL.170.9.4483

26 December 2023

Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability. Copolymer 1 Multiple Sclerosis Study Group

28

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Effect of copolymer-1 on serial gadolinium-enhanced MRI in relapsing remitting multiple sclerosis

29

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Sustained clinical benefits of glatiramer acetate in relapsing multiple sclerosis patients observed for 6 years. Copolymer 1 Multiple Sclerosis Study Group

30

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Mechanisms of action of glatiramer acetate in multiple sclerosis

31

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells--specificity and promiscuity.

32

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Bystander suppression of experimental autoimmune encephalomyelitis by T cell lines and clones of the Th2 type induced by copolymer 1

34

1 reference

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26 December 2023

Specific inhibition of the T-cell response to myelin basic protein by the synthetic copolymer Cop 1

35

1 reference

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Synthetic copolymer 1 inhibits human T-cell lines specific for myelin basic protein

36

1 reference

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26 December 2023

Copolymer 1 acts against the immunodominant epitope 82-100 of myelin basic protein by T cell receptor antagonism in addition to major histocompatibility complex blocking

37

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis

38

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Specific Th2 cells accumulate in the central nervous system of mice protected against experimental autoimmune encephalomyelitis by copolymer 1

39

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Glatiramer acetate (copolymer-1)-specific, human T cell lines: cytokine profile and suppression of T cell lines reactive against myelin basic protein

40

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Glatiramer acetate (Copaxone) induces degenerate, Th2-polarized immune responses in patients with multiple sclerosis

41

1 reference

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26 December 2023

Mechanisms of immunomodulation by glatiramer acetate

42

1 reference

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26 December 2023

Treatment of multiple sclerosis with copolymer-1 (Copaxone): implicating mechanisms of Th1 to Th2/Th3 immune-deviation.

43

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Multiple sclerosis: comparison of copolymer-1- reactive T cell lines from treated and untreated subjects reveals cytokine shift from T helper 1 to T helper 2 cells

44

1 reference

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Oral tolerance with copolymer 1 for the treatment of multiple sclerosis

46

1 reference

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Lymphadenopathy in patients with multiple sclerosis undergoing treatment with glatiramer acetate

47

1 reference

10.4049/JIMMUNOL.170.9.4483

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26 December 2023

Glatiramer acetate (GA) induces IL-13/IL-5 secretion in naive T cells

48

1 reference

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Glatiramer acetate and IFN-beta act on dendritic cells in multiple sclerosis

49

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Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

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Glatiramer acetate blocks interleukin-1-dependent nuclear factor-kappaB activation and RANTES expression in human U-251 MG astroglial cells

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Dendritic cell survival and maturation are regulated by different signaling pathways.

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1 reference

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The NF-kappa B and I kappa B proteins: new discoveries and insights

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26 December 2023

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10.4049/JIMMUNOL.170.9.4483

1 reference

Europe PubMed Central

2 December 2017

1 reference

Europe PubMed Central

2 December 2017

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