(Q44420167)

2 December 2017

title

Hammerhead ribozyme-mediated destruction of nuclear foci in myotonic dystrophy myoblasts (English)

1 reference

trinucleotide repeat expansion

2 December 2017

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1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12718910

28 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1525-0016(03)00068-6

28 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1525-0016(03)00068-6

28 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1525-0016(03)00068-6

28 December 2023

author name string

Marc-André Langlois

1

1 reference

2 December 2017

Nan Sook Lee

2

1 reference

2 December 2017

Jack Puymirat

4

1 reference

2 December 2017

John J. Rossi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12718910

28 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12718910

28 December 2023

publication date

1 May 2003

1 reference

full work available at URL

2 December 2017

http://www.cell.com/article/S1525001603000686/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12718910

https://api.elsevier.com/content/article/PII:S1525001603000686?httpAccept=text/xml

28 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1525-0016(03)00068-6

https://api.elsevier.com/content/article/PII:S1525001603000686?httpAccept=text/plain

28 December 2023

1 reference

https://api.crossref.org/works/10.1016/S1525-0016(03)00068-6

28 December 2023

1 reference

2 December 2017

volume

7

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2 December 2017

issue

5 Pt 1

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2 December 2017

page(s)

670-680

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Myotonic dystrophy mutation: an unstable CTG repeat in the 3' untranslated region of the gene

2 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Deconstructing myotonic dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Transcriptional abnormality in myotonic dystrophy affects DMPK but not neighboring genes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Biomedicine. Reconstructing myotonic dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Decreased levels of myotonic dystrophy protein kinase (DMPK) and delayed differentiation in human myotonic dystrophy myoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Expansion of the myotonic dystrophy CTG repeat reduces expression of the flanking DMAHP gene

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Myotonic dystrophy is associated with a reduced level of RNA from the DMWD allele adjacent to the expanded repeat

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Reduced expression of DMAHP/SIX5 gene in myotonic dystrophy muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Myotonic dystrophy: tissue-specific effect of somatic CTG expansions on allele-specific DMAHP/SIX5 expression.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Mice deficient in Six5 develop cataracts: implications for myotonic dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Mice transgenic for the human myotonic dystrophy region with expanded CTG repeats display muscular and brain abnormalities.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Muscleblind localizes to nuclear foci of aberrant RNA in myotonic dystrophy types 1 and 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Ribozyme structures and mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Ribozyme-mediated inhibition of HIV 1 suggests nucleolar trafficking of HIV-1 RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Generality of the NUX rule: kinetic analysis of the results of systematic mutations in the trinucleotide at the cleavage site of hammerhead ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Extending the cleavage rules for the hammerhead ribozyme: mutating adenosine15.1 to inosine15.1 changes the cleavage site specificity from N16.2U16.1H17 to N16.2C16.1H17.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Giant hairpins formed by CUG repeats in myotonic dystrophy messenger RNAs might sterically block RNA export through nuclear pores

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Constitutive and regulated modes of splicing produce six major myotonic dystrophy protein kinase (DMPK) isoforms with distinct properties

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Myotonic dystrophy: the role of the CUG triplet repeats in splicing of a novel DMPK exon and altered cytoplasmic DMPK mRNA isoform ratios

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Rapid determination and quantitation of the accessibility to native RNAs by antisense oligodeoxynucleotides in murine cell extracts

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Functional colocalization of ribozymes and target mRNAs in Drosophila oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Detection of antisense and ribozyme accessible sites on native mRNAs: application to NCOA3 mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

tRNA nuclear transport: defining the critical regions of human tRNAimet by point mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Expression of small, therapeutic RNAs in human cell nuclei.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Generation of long read-through transcriptsin vivoandin vitroby deletion of 3′ termination and processing sequences in the human tRNAimetgene

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900068-6

7 January 2021

Prediction of RNA secondary structure by energy minimization

34

1 reference

https://api.crossref.org/works/10.1016/S1525-0016(03)00068-6

28 December 2023

Identifiers

1 reference

2 December 2017

1 reference