(Q44428550)

2 December 2017

title

2,4-disubstituted pyrimidines: a novel class of KDR kinase inhibitors (English)

1 reference

2 December 2017

2,4-Disubstituted pyrimidines: A novel class of KDR kinase inhibitors (English)

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

30 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

30 December 2023

pharmaceutical science

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

30 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

30 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

30 December 2023

author name string

Peter J. Manley

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729639

30 December 2023

Adrienne E. Balitza

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729639

30 December 2023

Mark T. Bilodeau

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729639

30 December 2023

Kathleen E. Coll

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729639

30 December 2023

George D. Hartman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729639

30 December 2023

Rosemary C. McFall

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729639

30 December 2023

Keith W. Rickert

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729639

30 December 2023

Leonard D. Rodman

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729639

30 December 2023

Kenneth A. Thomas

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12729639

30 December 2023

language of work or name

English

0 references

publication date

1 May 2003

1 reference

2 December 2017

19 May 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12729639

full work available at URL

30 December 2023

https://api.elsevier.com/content/article/PII:S0960894X03002440?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

https://api.elsevier.com/content/article/PII:S0960894X03002440?httpAccept=text/plain

30 December 2023

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

Bioorganic & Medicinal Chemistry Letters

30 December 2023

published in

1 reference

2 December 2017

volume

13

1 reference

2 December 2017

issue

10

1 reference

2 December 2017

page(s)

1673-1677

1 reference

Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells

2 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

The angiogenic pathway ?vascular endothelial growth factor/flk-1(KDR)-receptor? in rheumatoid arthritis and osteoarthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

The role of VEGF and thrombospondins in skin angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Angiogenesis in cancer and other diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Angiogenesis in cancer, vascular, rheumatoid and other disease

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Vascular endothelial growth factor, a potent and selective angiogenic agent

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Kinase insert domain-containing receptor kinase inhibitors as anti-angiogenic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Synthesis and initial SAR studies of 3,6-disubstituted pyrazolo[1,5-a]pyrimidines: a new class of KDR kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Optimization of a pyrazolo[1,5-a]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Vascular endothelial growth factor receptor KDR tyrosine kinase activity is increased by autophosphorylation of two activation loop tyrosine residues

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

Strategies toward the design of novel and selective protein tyrosine kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900244-0

7 January 2021

8

60

203

Veikkola

2000

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

30 December 2023

12

59

99

Fong

1999

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

30 December 2023

13

60

4819

Drevs

2000

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(03)00244-0

30 December 2023

Identifiers

1 reference

2 December 2017

1 reference