(Q44439495)

3 December 2017

title

Probing cofactor specificity in phenylalanine hydroxylase by molecular dynamics simulations (English)

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3 December 2017

2

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3 December 2017

Knut Teigen

1

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3 December 2017

publication date

1 June 2003

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Journal of Biomolecular Structure and Dynamics

3 December 2017

published in

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3 December 2017

volume

20

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3 December 2017

issue

6

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3 December 2017

page(s)

733-740

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describes a project that uses

3 December 2017

molecular dynamics simulation

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based on heuristic

inferred from title

cites work

Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease-Related Mutant Forms

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Coordinate regulation of tetrahydrobiopterin turnover and phenylalanine hydroxylase activity in rat liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

The structural basis of the recognition of phenylalanine and pterin cofactors by phenylalanine hydroxylase: implications for the catalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

The structural basis of phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Conformation of the substrate and pterin cofactor bound to human tryptophan hydroxylase. Important role of Phe313 in substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Modulation by pterins of the phosphorylation and phenylalanine activation of phenylalanine 4-mono-oxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Regulatory properties of phenylalanine, tyrosine and tryptophan hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Structural basis of autoregulation of phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

An all atom force field for simulations of proteins and nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Essential role of the N-terminal autoregulatory sequence in the regulation of phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Mutagenesis of the regulatory domain of phenylalanine hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

Pterin-Dependent Amino Acid Hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2003.10506889

10.1080/07391102.2003.10506889

21 January 2018

Identifiers

DOI

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3 December 2017

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