(Q44462624)

3 December 2017

Bezafibrate is a dual ligand for PPARalpha and PPARbeta: studies using null mice (English)

1 reference

3 December 2017

Jeffrey M Peters

1

1 reference

3 December 2017

Toshifumi Aoyama

series ordinal

2

1 reference

3 December 2017

Amanda M Burns

series ordinal

3

1 reference

3 December 2017

Frank J Gonzalez

series ordinal

4

1 reference

3 December 2017

1 June 2003

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3 December 2017

10

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Biochimica et Biophysica Acta

inferred from page(s)

published in

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3 December 2017

1632

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3 December 2017

1-3

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3 December 2017

80-89

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Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

3 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Identification of two mPPAR related receptors and evidence for the existence of five subfamily members

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

A human peroxisome-proliferator-activated receptor-gamma is activated by inducers of adipogenesis, including thiazolidinedione drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferation and nongenotoxic carcinogenesis: commentary on a symposium

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Phytanic acid activates the peroxisome proliferator-activated receptor alpha (PPARalpha) in sterol carrier protein 2-/ sterol carrier protein x-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferator-activated receptor beta regulates acyl-CoA synthetase 2 in reaggregated rat brain cell cultures

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Conjugated linoleic acid activates peroxisome proliferator-activated receptor alpha and beta subtypes but does not induce hepatic peroxisome proliferation in Sprague-Dawley rats

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Hepatic expression of acute-phase protein genes during carcinogenesis induced by peroxisome proliferators

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Comparison of dose-response relationships for induction of lipid metabolizing and growth regulatory genes by peroxisome proliferators in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Fatty acids activate transcription of the muscle carnitine palmitoyltransferase I gene in cardiac myocytes via the peroxisome proliferator-activated receptor alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Down-regulation of cytochrome P450 2C family members and positive acute-phase response gene expression by peroxisome proliferator chemicals.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

The PPARalpha-leukotriene B4 pathway to inflammation control.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

The role of the peroxisome proliferator-activated receptor alpha (PPAR alpha) in the control of cardiac lipid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Tissue-specific induction of 17 beta-hydroxysteroid dehydrogenase type IV by peroxisome proliferator chemicals is dependent on the peroxisome proliferator-activated receptor alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Sex-dependent regulation of hepatic peroxisome proliferation in mice by trichloroethylene via peroxisome proliferator-activated receptor alpha (PPARalpha)

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Role of peroxisome proliferator-activated receptor alpha in altered cell cycle regulation in mouse liver.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome Proliferator-activated Receptor α Activation Modulates Cellular Redox Status, Represses Nuclear Factor-κB Signaling, and Reduces Inflammatory Cytokine Production in Aging

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Influence of peroxisome proliferator-activated receptor alpha on ubiquinone biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Receptor and nonreceptor-mediated organ-specific toxicity of di(2-ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Identification of a novel peroxisome proliferator responsive cDNA isolated from rat hepatocytes as the zinc-finger protein ZFP-37

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

The peroxisome proliferator-activated receptor alpha (PPARalpha) regulates bile acid biosynthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Adaptive increase in pyruvate dehydrogenase kinase 4 during starvation is mediated by peroxisome proliferator-activated receptor alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Responses of insulin-like growth factor (IGF)-I and IGF-binding proteins to nutritional status in peroxisome proliferator-activated receptor-alpha knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated wi

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferator-activated receptor-alpha regulates lipid homeostasis, but is not associated with obesity: studies with congenic mouse lines

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

PPAR gamma is required for placental, cardiac, and adipose tissue development

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Bezafibrate reduces mRNA levels of adipocyte markers and increases fatty acid oxidation in primary culture of adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Bezafibrate induces acyl-CoA oxidase mRNA levels and fatty acid peroxisomal beta-oxidation in rat white adipose tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferator-activated receptors gamma and alpha mediate in vivo regulation of uncoupling protein (UCP-1, UCP-2, UCP-3) gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor gamma

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

PPARalpha activation by Wy 14643 induces transactivation of the rat UCP-1 promoter without increasing UCP-1 mRNA levels and attenuates PPARgamma-mediated increases in UCP-1 mRNA levels induced by rosiglitazone in fetal rat brown adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferator-activated receptor alpha (PPARalpha) activators, bezafibrate and Wy-14,643, increase uncoupling protein-3 mRNA levels without modifying the mitochondrial membrane potential in primary culture of rat preadipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferator-activated receptor-beta signaling contributes to enhanced proliferation of hepatic stellate cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Expression of the peroxisome proliferator-activated receptor (PPAR) in the mouse colonic mucosa.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Lipoprotein lipase gene expression in THP-1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Alterations in Thyroid Status Modulate Apolipoprotein, Hepatic Triglyceride Lipase, and Low Density Lipoprotein Receptor in Rats*

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Developmental and pharmacological regulation of apolipoprotein C-II gene expression. Comparison with apo C-I and apo C-III gene regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Evidence for peroxisome proliferator-activated receptor (PPAR)alpha-independent peroxisome proliferation: effects of PPARgamma/delta-specific agonists in PPARalpha-null mice

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Mode of action of peroxisome proliferators as hypolipidemic drugs. Suppression of apolipoprotein C-III.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor alpha and gamma ligands

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Uncoupling protein-3 mRNA levels are increased in white adipose tissue and skeletal muscle of bezafibrate-treated rats

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Mechanism for peroxisome proliferator-activated receptor-alpha activator-induced up-regulation of UCP2 mRNA in rodent hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1388-1981%2803%2900065-9

7 January 2021

10.1016/S1388-1981(03)00065-9

Identifiers

DOI

1 reference

3 December 2017

1 reference