(Q44466226)

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Enforced expression of the tumor suppressor p53 renders human leukemia cells (U937) more sensitive to 1-[beta-D-arabinofuranosyl]cytosine (ara-C)-induced apoptosis

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Europe PubMed Central

PubMed publication ID

3 December 2017

Enforced expression of the tumor suppressor p53 renders human leukemia cells (U937) more sensitive to 1-[beta-D-arabinofuranosyl]cytosine (ara-C)-induced apoptosis (English)

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Europe PubMed Central

PubMed publication ID

3 December 2017

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Roy H Decker

1

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Europe PubMed Central

PubMed publication ID

3 December 2017

Jay Levin

2

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Europe PubMed Central

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3 December 2017

Lora B Kramer

3

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Europe PubMed Central

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3 December 2017

Yun Dai

4

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Europe PubMed Central

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3 December 2017

Steven Grant

5

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Europe PubMed Central

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3 December 2017

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publication date

1 June 2003

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3 December 2017

Biochemical Pharmacology

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Europe PubMed Central

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3 December 2017

65

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Europe PubMed Central

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3 December 2017

12

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Europe PubMed Central

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3 December 2017

1997-2008

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Europe PubMed Central

PubMed publication ID

3 December 2017

A new look at the role of p53 in leukemia cell sensitivity to chemotherapy

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Identification of p53 as a sequence-specific DNA-binding protein

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

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WAF1, a potential mediator of p53 tumor suppression

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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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Genetic determinants of p53-induced apoptosis and growth arrest

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Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

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p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53.

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E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis

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Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

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Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment

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Relationship between nitrogen mustard drug resistance in B-cell chronic lymphocytic leukemia (B-CLL) and protein expression of Bcl-2, Bax, Bcl-X and p53

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Acute myelogenous leukemia: current treatment and future directions.

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Establishment and characterization of a human histiocytic lymphoma cell line (U-937)

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Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

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Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay

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Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

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Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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Bax involvement in p53-mediated neuronal cell death

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A model for p53-induced apoptosis

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Suppression of mismatched mutation by p53: a mechanism for guarding genomic integrity

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Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia

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Changes in c-Jun but not Bcl-2 family proteins in p53-dependent apoptosis of mouse cerebellar granule neurons induced by DNA damaging agent bleomycin

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Adenovirus-mediated transfer of wild-type p53 gene sensitizes TNF resistant MCF7 derivatives to the cytotoxic effect of this cytokine: relationship with c-myc and Rb.

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis

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7 January 2021

p21Cip1/WAF1 is important for differentiation and survival of U937 cells

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7 January 2021

Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53.

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Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta

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Identifiers

10.1016/S0006-2952(03)00149-7

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Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

ResearchGate publication ID

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